CAS 194034-61-2

6-Chloro-9-(3,5-di-O-acetyl-2-O-methyl-β-D-ribofuranosyl)-9H-purine

CAS: 194034-61-2

Nucleoside Derivatives - 2’-Modified nucleosides, Halo-nucleosides

Formel: C₁₅H₁₇ClN₄O₆

Farbe und Form: Solid

Molekulargewicht: 384.77

Ref: TM-TNU1158

9-(3',5'-Di-O-acetyl-2'-O-methyl-b-D-ribofuranosyl)-6-chloropurine

CAS: 194034-61-2

9-(3',5'-Di-O-acetyl-2'-O-methyl-b-D-ribofuranosyl)-6-chloropurine is a novel and high quality antiviral monophosphate deoxyribonucleoside. It is synthesized from 2'-deoxyadenosine monophosphate, 2'-deoxycytidine monophosphate, and 6-chloropurine by the phosphorylation of nucleosides with a modified phosphoramidite method. The polymerase chain reaction (PCR) amplification of HIV DNA was inhibited with this compound in vitro. This drug also has anticancer activity when it is used in combination with other chemotherapeutic drugs such as gemcitabine, cisplatin, and paclitaxel.

Reinheit: Min. 95%

Ref: 3D-ND163039