CAS 2097493-39-3

PDE2 inhibitor 6

CAS: 2097493-39-3

PDE2 inhibitor6 (Compound 1) is an orally active phosphodiesterase (PDE) inhibitor, effectively inhibiting PDE2A, PDE3B, and PDE10A2 with IC50 values of 0.95 nM, 6.17 μM (pIC50=5.21), and 87.1 nM (pIC50=7.06), respectively. It modulates AMPA receptor activity, enhances synaptic plasticity, and improves learning and memory in rat models. Furthermore, PDE2 inhibitor6 possesses blood-brain barrier permeability.

Formel: C₂₀H₂₂F₂N₆O

Farbe und Form: Solid

Molekulargewicht: 400.425

Ref: TM-T206498