CAS 2101958-02-3

squarunkinA

CAS: 2101958-02-3

squarunkinA

Reinheit: ≥98%

Molekulargewicht: 523.55g/mol

Ref: 54-BUP06617

squarunkinA

CAS: 2101958-02-3

squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-

Formel: C₂₅H₃₂F₃N₅O₄

Reinheit: 99.29%

Farbe und Form: Solid

Molekulargewicht: 523.55

Ref: TM-T9002

Squarunkin A

CAS: 2101958-02-3

Selective inhibitor of the interaction between the UNC119 chaperone and its cargo. Squarunkin A inhibits activation of Src kinase by interrupting the interaction between the myristoylated peptide at the N-terminus of the Src kinase and UNC119A chaperone (IC50 = 10 nM). Squarunkin A impairs the UNC119-mediated enrichment of plasma membrane with non-receptor protein tyrosine kinase Src, resulting in the decrease in Src autophosphorylation and decreased oncogenic Src signalling.

Formel: C₂₅H₃₂F₃N₅O₄

Reinheit: Min. 95%

Farbe und Form: Solid

Molekulargewicht: 523.55 g/mol

Ref: 3D-BS168651