CAS 2117404-84-7

BAY-677

CAS: 2117404-84-7

BAY-677, an inactive counterpart to BAY-678, inhibits human neutrophil elastase with 20 nM IC50 and is an SGC-nominated probe.

Formel: C₂₀H₁₅F₃N₄O₂

Farbe und Form: Solid

Molekulargewicht: 400.35

Ref: TM-T10473L

BAY 677

CAS: 2117404-84-7

Bay 677 is a potent inhibitor of the human organic anion transporter (hOAT) that is currently being investigated for its effects on acute lung injury. Bay 677 has been shown to have a pharmacokinetic profile that is suitable for oral administration in humans, while methyl sulfone is metabolized through oxidative pathways. Bay 677 also has a high affinity for hOAT and disrupts the transport of organic anions across the cell membrane, which may be responsible for its anti-inflammatory effects.

Formel: C₂₀H₁₅F₃N₄O₂

Reinheit: Min. 95%

Molekulargewicht: 400.35 g/mol

Ref: 3D-BB163663