CAS 2227480-51-3

Ponatinib N-Oxide

CAS: 2227480-51-3

Formel: C₂₉H₂₇F₃N₆O₂

Farbe und Form: Yellow Solid

Molekulargewicht: 548.57

Ref: 4Z-P-123004

Ponatinib N-Oxide

Kontrolliertes Produkt

CAS: 2227480-51-3

Applications Ponatinib N-Oxide is derived from Ponatinib (P688250), which is a tyrosine kinase inhibitors (TKI) and used to treat chronic myeloid leukemia (CML) (1,2,3). Ponatinib is also used in combination with other drugs, such as forskolin, to combat TKI resistance in patient with CML (3), targeted drug in small-cell lung cancer. Potent FAK inhibitor. FGFR/VEGFR/Bcr-Abl inhibitor. It is a COVID19-related research product.
References De L., et al.: J. Pharmacol. Exp. Ther., 363, 12-19 (2017), Arts, F. A., et al.: Hum. Mol. Genet., 26, 1801-1810 (2017)

Formel: C₂₉H₂₇F₃N₆O₂

Farbe und Form: Neat

Molekulargewicht: 548.56

Ref: TR-P688260

Ponatinib N-Oxide

CAS: 2227480-51-3

Formel: C₂₉H₂₇F₃N₆O₂

Molekulargewicht: 548.57

Ref: ST-EA-CP-P94006