CAS 2237230-21-4

EGFR/HER2-IN-12

Formel: C₂₅H₁₇ClN₄O₃S

Synonyme:

• EGFR/HER2-IN-12
• Thieno[2,3-d]pyrimidin-4-amine, N-[3-chloro-4-(3-methylphenoxy)phenyl]-6-(4-nitrophenyl)-

EGFR/HER2-IN-12

CAS: 2237230-21-4

EGFR/HER2-IN-12 (compound 14b) serves as a dual inhibitor targeting EGFR and HER2, demonstrating 81% and 51% inhibition respectively at a concentration of 10 μM. This compound exhibits minimal toxicity towards A431 and MDA-MB-361 cancer cells [1].

Formel: C₂₅H₁₇ClN₄O₃S

Molekulargewicht: 488.95

Ref: TM-T86353