CAS 2244702-64-3

TGase2-IN-1

CAS: 2244702-64-3

TGase2-IN-1 (Compound 22) is an orally effective TGase2 inhibitor with an IC50 of 1.12 µM. It inhibits TGase2 in human retinal microvascular endothelial cells with a strikingly lower IC50 of 0.07 µM. The oral bioavailability of TGase2-IN-1 is 74.6%. Additionally, it can suppress retinal vascular leakage in a mouse model of diabetes induced by Streptozotocin.

Formel: C₂₃H₂₅N₃O₃

Farbe und Form: Solid

Molekulargewicht: 391.46

Ref: TM-T201596