CAS: 23214-92-8 - Doxorubicin

Formel: C₂₇H₂₉NO₁₁

InChl: InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1

InChI Key: InChIKey=AOJJSUZBOXZQNB-TZSSRYMLSA-N

SMILES: O=C1C=2C=CC=C(OC)C2C(=O)C=3C(O)=C4C(=C(O)C13)CC(O)(C(=O)CO)CC4OC5OC(C)C(O)C(N)C5

Synonyme:

• (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
• (7S,9S)-7-[(2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,1 1-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
• (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
• (8S-cis)-10-(3-Amino-2,3,6-Trideoxy-alpha-L-Lyxo-Hexopyranosyl)Oxy-7,8,9,10-Tetrahydro-6,8,11-Trihydroxy-8-(Hydroxyacetyl)-1-Methoxy-5,12-Naphthacenedione
• 10-((3-Amino-2,3,6-trideoxy-alpha-L-lyso-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
• 14-Hydroxydaunomycin
• 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)-
• 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-
• 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-
• 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)-
• 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-
• 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-
• Adiblastine (Hydrochloride Salt)
• Adriablastine (Hydrochloride Salt)
• Adriablatina (Hydrochloride Salt)
• Adriacin
• Adriacin (hydrochloride salt)
• Adriamycin PFS
• Adriamycin PFS (hydrochloride salt)
• Adriamycin RDF
• Adriamycin RDF (hydrochloride salt)
• Adriblastin
• Adriblastina
• Adriblastina (hydrochloride salt)
• Adriblatina (Hydrochloride Salt)
• Ameisu
• Biotransdox
• Caelix
• Caelyx
• Doxil
• Doxorrubicina
• Doxorubicin
• Doxorubicin hydrochloride (hydrochloride salt)
• Doxorubicine
• Evacet
• Farmablastina (hydrochloride salt)
• Hydroxydaunomycin
• Hydroxydaunomycin hydrochloride (hydrochloride salt)
• Hydroxydaunorubicin
• Hydroxydaunorubicin hydrochloride (hydrochloride salt)
• Liporubicin
• Livatag
• Nsc 123127
• Oncodox
• Pk 2
• Rubex
• Rubex (hydrochloride salt)
• Rubidox
• (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

Doxorubicin Hydrochloride

CAS: 23214-92-825316-40-9

• Formel: C₂₇H₂₉NO₁₁·HCl
• Reinheit: >95.0%(HPLC)
• Farbe und Form: Light yellow to Brown powder to crystal
• Molekulargewicht: 579.98

5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)-

CAS: 23214-92-8

• Formel: C₂₇H₂₉NO₁₁
• Reinheit: 97%
• Farbe und Form: Solid
• Molekulargewicht: 543.5193

Doxorubicin Free Base

CAS: 23214-92-8

• Farbe und Form: Solid
• Molekulargewicht: 543.52g/mol

Doxorubicin, free base

CAS: 23214-92-8

• Formel: C₂₇H₂₉NO₁₁
• Reinheit: (HPLC) 98.0 - 102.0 % (anhydrous basis)
• Farbe und Form: Orange-red powder
• Molekulargewicht: 543.52

Doxorubicin

CAS: 23214-92-8

Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.

• Formel: C₂₇H₂₉NO₁₁
• Reinheit: 98%
• Farbe und Form: Red Crystalline Solid Solid
• Molekulargewicht: 543.52