CAS 2361-96-8

Ethylester von Acetyl-L-phenylalanin

Beschreibung:

Ethylester von Acetyl-L-phenylalanin, mit der CAS-Nummer 2361-96-8, ist ein Esterderivat der Aminosäure Phenylalanin. Diese Verbindung weist eine Acetylgruppe auf, die an die Aminogruppe von Phenylalanin gebunden ist, sowie eine Ethylestergruppe am Ende der Carbonsäure. Es handelt sich typischerweise um einen weißen bis schmutzig-weißen kristallinen Feststoff, der in organischen Lösungsmitteln wie Ethanol und Methanol löslich ist, jedoch weniger gut in Wasser. Das Vorhandensein der Acetylgruppe erhöht seine Lipophilie, was seine biologische Aktivität und Absorptionseigenschaften beeinflussen kann. Ethylester von Acetyl-L-phenylalanin wird häufig im Kontext der Peptidsynthese und als potenzielles Zwischenprodukt in der Herstellung von Arzneimitteln untersucht. Seine strukturellen Eigenschaften ermöglichen es ihm, an verschiedenen chemischen Reaktionen teilzunehmen, was ihn zu einer wertvollen Verbindung in der organischen Synthese und der medizinischen Chemie macht. Darüber hinaus kann es aufgrund seiner Aminosäurenstruktur einige biologische Aktivitäten aufweisen, obwohl spezifische Anwendungen je nach laufender Forschung und Entwicklung variieren können.

Formel: C₁₃H₁₇NO₃

InChl: InChI=1S/C13H17NO3/c1-3-17-13(16)12(14-10(2)15)9-11-7-5-4-6-8-11/h4-8,12H,3,9H2,1-2H3,(H,14,15)/t12-/m0/s1

InChI Key: InChIKey=YIVZYFDBEPMPNL-LBPRGKRZSA-N

SMILES: [C@H](CC1=CC=CC=C1)(C(OCC)=O)NC(C)=O

Synonyme:

• <span class="text-smallcaps">L</span>-N-Acetylphenylalanine ethyl ester
• <span class="text-smallcaps">L</span>-Phenylalanine, N-acetyl-, ethyl ester
• Ac-Phe-OEt
• Acetyl-<span class="text-smallcaps">L</span>-phenylalanine ethyl ester
• Acetylphenylalanine ethyl ester
• Alanine, N-acetyl-3-phenyl-, ethyl ester, <span class="text-smallcaps">L</span>-
• Ethyl N-acetyl-<span class="text-smallcaps">L</span>-phenylalaninate
• N-Acetyl-<span class="text-smallcaps">L</span>-phenylalanine ethyl ester
• N-Acetylphenylalanine ethyl ester
• ethyl N-acetyl-3-phenyl-L-alaninate
• ethyl N-acetyl-L-phenylalaninate
• ethyl N-acetylphenylalaninate
• L-Phenylalanine, N-acetyl-, ethyl ester
• N-Acetyl-L-phenylalanine ethyl ester
• Acetyl-L-phenylalanine ethyl ester

(S)-Ethyl 2-acetamido-3-phenylpropanoate

CAS: 2361-96-8

Formel: C₁₃H₁₇NO₃

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 235.2790

Ref: IN-DA003SP2

N-Acetyl-L-Phenylalanine Ethyl Ester

CAS: 2361-96-8

N-Acetyl-L-Phenylalanine Ethyl Ester

Reinheit: 98%

Molekulargewicht: 235.28g/mol

Ref: 54-OR1014236

Ac-Phe-OEt

CAS: 2361-96-8

Formel: C₁₃H₁₇NO₃

Reinheit: >98.0%(HPLC)

Farbe und Form: White to Light yellow powder to crystal

Molekulargewicht: 235.28

Ref: 3B-A3498

Ac-Thz-Tle-Leu-Gln-MCA

CAS: 2361-96-8

A prototype fluorogenic substrate targeting the SARS-CoV and SARS-CoV-2 Main Protease (Mpro). The main protease (Mpro­), also called endopeptidase C30 or 3C-like proteinase (3CLpro), controls viral replication activities and is a prime therapeutical target. Both substrates and inhibitors of SARS-CoV-2 Mpro are currently of interest to researchers of the coronavirus. This product can be used as a Prototype Fluorescence Substrate for SARS-CoV Mpro/SARS-CoV-2 Mpro Proteases.

Formel: C₁₃H₁₇NO₃

Reinheit: Min. 95%

Molekulargewicht: 235.28 g/mol

Ref: 3D-SFP-3251-V

Acetyl-L-phenylalanine Ethyl Ester

Kontrolliertes Produkt

CAS: 2361-96-8

Applications Acetyl-L-phenylalanine ethyl ester is a derivative of L-Phenylalanine (P319415), a nonpolar, essential amino acid that naturally occurs in the human body and is also used to treat patients with depression. Acetyl-L-phenylalanine ethyl ester is also used to inhibit pepsin-catalyzed reactions.
References Auer, H. & Doty, P.: Biochemistry, 5, 1708 (1966); Birkmayer, W., et al.: J. Neural Transm., 59, 81 (1984); Borison, R., et al.: Res. Commun. Chem. Path., 21, 363 (1978); Kitson, T., et al.: Biochem. J., 122, 241 (1971)

Formel: C₁₃H₁₇NO₃

Farbe und Form: Neat

Molekulargewicht: 235.28

Ref: TR-A187950

(S)-Ethyl 2-acetamido-3-phenylpropanoate

CAS: 2361-96-8

Formel: C₁₃H₁₇NO₃

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 235.283

Ref: 10-F224477

Acetyl-L-phenylalanine ethyl ester

CAS: 2361-96-8

Acetyl-L-phenylalanine ethyl ester is a substrate analogue that competes with the natural substrate, L-phenylalanine, for binding sites on the enzyme. The acetyl group of acetyl-L-phenylalanine ethyl ester reacts with the amino acid residues of L-phenylalanine to form covalent linkages. This prevents the enzyme from catalyzing reactions involving L-phenylalanine and other substrates. Acetyl-L-phenylalanine ethyl ester binds to cytochalasin B and inhibits its ability to bind to actin filaments, thus inhibiting cell growth. The high salt concentration in this experiment allows for separation of the protein from other cellular components by sephadex g-100 chromatography. Kinetic studies have been done on human serum albumin, which is a protein that can bind acetyl-L-phenylalanine ethl ester with a

Formel: C₁₃H₁₇NO₃

Reinheit: Min. 95%

Molekulargewicht: 235.28 g/mol

Ref: 3D-FA47441

Ac-Phe-OEt

CAS: 2361-96-8

Ac-Phe-OEt is a covalently conjugated bifunctional peptide that has been synthesized by linking the amino acid phenylalanine to the amino acid ethyl ester of oleic acid. Ac-Phe-OEt exhibits a high affinity for bacterial serine proteases (Km=0.1 μM) and lysine residues (Ki=4 μM). This peptide also binds to immobilized cytochalasin, which prevents the formation of amyloid fibrils. Ac-Phe-OEt can be used in enzyme catalysis as an inhibitor or competitive inhibitor, as well as being immobilized on surfaces. The kinetic data suggests that Ac-Phe-OEt competes with lysine residues for binding to bacterial serine proteases and inhibits their activity.

Formel: C₁₃H₁₇NO₃

Reinheit: Min. 95%

Molekulargewicht: 235.28 g/mol

Ref: 3D-SFE-3006