CAS 2415-24-9

Catalpol

Beschreibung:

Catalpol, mit der CAS-Nummer 2415-24-9, ist ein natürlich vorkommendes Iridoid-Glycosid, das hauptsächlich in verschiedenen Pflanzenarten, insbesondere in der Gattung Rehmannia, vorkommt. Es ist durch seine chemische Struktur gekennzeichnet, die ein Glucose-Moiety enthält, das an einen Iridoid-Kern gebunden ist. Catalpol ist bekannt für seine potenziellen pharmakologischen Eigenschaften, einschließlich entzündungshemmender, antioxidativer und neuroprotektiver Wirkungen. Es wurde für seine Rolle in der traditionellen Medizin untersucht, insbesondere in chinesischen Kräuterheilmitteln, wo man glaubt, dass es die Nierengesundheit unterstützt und die allgemeine Vitalität verbessert. Die Verbindung zeigt Löslichkeit in polaren Lösungsmitteln, was für Glycoside typisch ist, und ihre Stabilität kann von Faktoren wie pH und Temperatur beeinflusst werden. Die Forschung zu Catalpol untersucht weiterhin seine Wirkmechanismen und potenziellen therapeutischen Anwendungen, was es zu einem interessanten Thema sowohl in der Pharmakognosie als auch in der medizinischen Chemie macht.

Formel: C₁₅H₂₂O₁₀

InChl: InChI=1S/C15H22O10/c16-3-6-9(19)10(20)11(21)14(23-6)24-13-7-5(1-2-22-13)8(18)12-15(7,4-17)25-12/h1-2,5-14,16-21H,3-4H2/t5-,6-,7-,8+,9-,10+,11-,12+,13+,14+,15-/m1/s1

InChI Key: InChIKey=LHDWRKICQLTVDL-PZYDOOQISA-N

SMILES: C(O)[C@@]12[C@@]3([C@]([C@H](O)[C@@]1(O2)[H])(C=CO[C@H]3O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[H])[H]

Synonyme:

• (1AS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl-beta-D-glucopyranoside
• (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-<span class="text-smallcaps">D</span>-glucopyranoside
• (1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[4,5]cyclopenta[1,2-c]pyran-2-yl beta-D-glucopyranoside
• 6-Hydroxy-1A-(Hydroxymethyl)-1A,1B,2,5A,6,6A-Hexahydrooxireno[4,5]Cyclopenta[1,2-C]Pyran-2-Yl Hexopyranoside
• 7,8-Epoxyaucubin
• Aucubin 7,8-epoxide
• Catalpinoside
• Catalposide, des-p-hydroxybenzoyl-
• Catapol
• De(p-hydroxybenzoyl)catalposide
• beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy- 1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl, (1aS-(1a-alpha,1b-beta,2-beta,5a-beta,6-beta,6a-alpha))-
• beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl, (1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
• Catalpol
• β-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
• β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl

Catalpol

CAS: 2415-24-9

Catalpol analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formel: C₁₅H₂₂O₁₀

Reinheit: (HPLC) ≥99%

Farbe und Form: Powder

Molekulargewicht: 362.34

Ref: 11-0233S

CATALPOL CRS

CAS: 2415-24-9

CATALPOL CRS

Ref: 41-Y0002142

(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-D-glucopyranoside

CAS: 2415-24-9

Formel: C₉H₁₆O₄

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 188.2209

Ref: IN-DA0039M9

Catalpol

CAS: 2415-24-9

Catalpol (Catalpinoside) is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.

Formel: C₁₅H₂₂O₁₀

Reinheit: 99.74% - 99.89%

Farbe und Form: Powder

Molekulargewicht: 362.33

Ref: TM-T2780

Catalpol

CAS: 2415-24-9

Catalpol

Reinheit: ≥98%

Molekulargewicht: 362.33g/mol

Ref: 54-BUP00175

Catalpol

CAS: 2415-24-9

Formel: C₁₅H₂₂O₁₀

Reinheit: ≥ 96.5%

Farbe und Form: White, off-white or faint brown powder

Molekulargewicht: 362.33

Ref: 7W-GC8147

Catalpol

CAS: 2415-24-9

Catalpol

Reinheit: 98%

Molekulargewicht: 362.33g/mol

Ref: 54-OR1026446

Catalpol

CAS: 2415-24-9

Catalpol, an iridoid glucoside, has been reported to inhibit apoptosis of neuron and endothelial cells; the pretreatment of H9c2 cells with catalpol can be against H 2 O 2 -induced apoptosis, and the protective effect of catalpol involves the mitochondrial-dependent caspase pathway and is associated with increased Bcl-2 and decreased Bax expression.

Formel: C₁₅H₂₂O₁₀

Reinheit: 95%~99%

Farbe und Form: Powder

Molekulargewicht: 362.331

Ref: BP-BP0321

Catalpol

CAS: 2415-24-9

Formel: C₁₅H₂₂O₁₀

Reinheit: >95.0%(HPLC)

Farbe und Form: White to Light yellow powder to crystal

Molekulargewicht: 362.33

Ref: 3B-C3494

Catalpol

CAS: 2415-24-9

Natural glycoside

Formel: C₁₅H₂₂O₁₀

Reinheit: ≥ 98.0 % (HPLC)

Farbe und Form: Powder

Molekulargewicht: 362.33

Ref: 5G-89595

Catapol

CAS: 2415-24-9

Applications Catapol is an iridoid glucoside that has been shown to alleviate neuropathic pain.
References Gong, N. et al.: Neuripharmacol., 83, 31 (2014); Liu, Z. et al.: Curr. Bioact. COmp., 9, 306 (2013);

Formel: C₁₅H₂₂O₁₀

Farbe und Form: White To Off White

Molekulargewicht: 362.33

Ref: TR-C215150

Catalpol

CAS: 2415-24-9

Catalpol is an iridoid glycoside, which is a natural compound isolated primarily from the roots of the plant *Rehmannia glutinosa*. This compound is known for its various bioactive properties, functioning predominantly through its ability to modulate antioxidant pathways, regulate inflammatory responses, and exert neuroprotective effects. These modes of action are attributed to its capacity to influence cellular signaling pathways, such as the PI3K/Akt pathway, and to interact with reactive oxygen species (ROS), thereby mitigating oxidative stress.

Formel: C₁₅H₂₂O₁₀

Reinheit: Min. 95%

Farbe und Form: Powder

Molekulargewicht: 362.33 g/mol

Ref: 3D-MC08278

Catalpol

CAS: 2415-24-9

Reinheit: 98%

Molekulargewicht: 362.331

Ref: 10-F979677