CAS 2490686-86-5

WHN-88

CAS: 2490686-86-5

WHN-88, a Porcupine (PORCN) inhibitor, disrupts the palmitoylation of Wnt ligands, which inhibits their secretion and subsequent Wnt/β-catenin signaling. This compound has shown efficacy in reducing cancer cell stemness and suppressing the progression and development of breast tumors in MMTV-Wnt1 transgenic mice.

Formel: C₁₈H₁₃I₂N₃O₂

Farbe und Form: Solid

Molekulargewicht: 557.12

Ref: TM-T89881