CAS 2497585-50-7

SD-436

CAS: 2497585-50-7

SD-436

Reinheit: ≥98%

Molekulargewicht: 1248.2g/mol

Ref: 54-BUP22243

SD-436

CAS: 2497585-50-7

SD-436 is a selective and highly efficient STAT3 PROTAC degrader (DC50 = 0.5 μM), with an IC50 of 19 nM for STAT3, significantly higher than for STAT1/4/5/6. SD-436 depletes STAT3 and induces tumour regression in mouse leukaemia and lymphoma xenograft models.

Formel: C₅₈H₆₂F₄N₉O₁₄PS

Reinheit: 99.34%

Farbe und Form: Solid

Molekulargewicht: 1248.2

Ref: TM-T203395