CAS 2760328-82-1

IRAK1/4/pan-FLT3 Kinase-IN-1

CAS: 2760328-82-1

IRAK1/4/pan-FLT3 Kinase-IN-1 (Compound 31) is a potent inhibitor of IRAK1, IRAK4, and FLT3 kinases, demonstrating IC50 values of 5 nM for IRAK1, 0.6 nM for IRAK4, and less than 0.5 nM for FLT3. It exhibits favorable pharmacokinetic properties and holds promise for research in acute myeloid leukemia, with survival extension effects comparable to Gilteritinib.

Formel: C₂₁H₂₆FN₅O₂

Molekulargewicht: 399.46

Ref: TM-T203079