
CAS 290304-24-4
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4 Produkte.
5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[[2,3,6-trideoxy-3-[[[[4-(β-D-galactopyranosyloxy)-3-nitrophenyl]methoxy]carbonyl]amino]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-
CAS:Formel:C41H44N2O20Reinheit:98.72%Molekulargewicht:884.7895Daun02
CAS:Daun02 is the topoisomerase inhibitor Daunorubicin prodrug.Formel:C41H44N2O20Reinheit:98%Farbe und Form:SolidMolekulargewicht:884.79Daun02
CAS:A prodrug of the DNA-intercalating agent daunorubicin with anti-tumoral activity, used for suicide gene therapy and activity-dependent ablation of cells. Daun02 is an inactive form of the toxin, which gets activated upon cleavage with prodrug-activating enzyme β-galactosidase, yielding daunorubicin. Genetic constructs have been designed carrying the lacZ gene, coding for β-galactosidase, under control of application-specific promoters. The cells expressing the β-gal undergo cell death since the enzyme hydrolizes the prodrug into the active toxin.Formel:C41H44N2O20Reinheit:Min. 95%Farbe und Form:Red To Brown SolidMolekulargewicht:884.24874




