CAS 2911585-37-8

SILA-123

CAS: 2911585-37-8

SILA-123, an inhibitor of FLT3 (FLT3-WT: IC50=2.1 nM; FLT3-ITD: IC50=1.0 nM), induces cell apoptosis by hindering the cell cycle progression at the G0/G1 phase through the suppression of FLT3 phosphorylation and its downstream signaling pathways. This compound is utilized in the study of acute myeloid leukemia.

Formel: C₂₄H₂₅N₅O₂

Farbe und Form: Solid

Molekulargewicht: 415.49

Ref: TM-T200498