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CAS 3001361-04-9

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  • ALK5-IN-82
    Targetmol
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    ALK5-IN-82

    CAS:
    <p>ALK5-IN-82 is a potent and selective inhibitor of activin receptor-like kinase 5 (ALK5), demonstrating an IC50 value of 9.1 nM. This compound effectively suppresses the expression of α-smooth muscle actin (α-SMA), collagen I, and the proteinases tissue inhibitor of metalloproteinase 1 (TIMP-1) and matrix metalloproteinase 13 (MMP-13) in human umbilical vein endothelial cells induced by transforming growth factor-β. ALK5-IN-82 shows potential for use in research related to cardiac fibrosis.</p>
    Formel:C22H19N7OS
    Farbe und Form:Solid
    Molekulargewicht:429.50

    Ref: TM-T200604