CAS 3027608-60-9

NLRP3-IN-69

CAS: 3027608-60-9

NLRP3-IN-69 (Compound 23) inhibits the activation of NF-κBp65 and the formation of the NLRP3 inflammasome. It suppresses the overexpression of IL-1β, iNOS, and COX-2 induced by LPS, and inhibits the production of NO (IC50=5.66 μM), thereby demonstrating anti-inflammatory activity.

Formel: C₂₅H₂₄O₇

Farbe und Form: Solid

Molekulargewicht: 436.454

Ref: TM-T205524