CAS 3057263-82-5

1H-Pyrazolo[3,4-b]pyridine, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-

Formel: C₁₆H₁₂FN₅

Synonyme:

• 1H-Pyrazolo[3,4-b]pyridine, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-

CK1δ-IN-9

CAS: 3057263-82-5

CK1δ-IN-9 (Compound 8) is an inhibitor of casein kinase 1 (CK1), specifically targeting CK1δ with an IC50 of 1.4 nM. The compound also inhibits p38α and p38β with IC50 values of 0.25 μM and 0.78 μM, respectively. CK1δ-IN-9 exhibits favorable pharmacokinetic properties, including high oral bioavailability (70%) and moderate clearance.

Formel: C₁₆H₁₂FN₅

Farbe und Form: Solid

Molekulargewicht: 293.298

Ref: TM-T205445