CAS 331947-66-1

(R)-Tolvaptan

CAS: 331947-66-1

Formel: C₂₆H₂₅ClN₂O₃

Farbe und Form: White To Off-White Solid

Molekulargewicht: 448.95

Ref: 4Z-T-697

(R)-(+)-Tolvaptan

Kontrolliertes Produkt

CAS: 331947-66-1

Applications An enantiomer of Tolvaptan. It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
References Paterna, S., et al.: Eur. J. Heart Fail, 2, 305 (2000), Udelson, J., et al.: Circulation, 104, 2417 (2001), Goldsmith, S., et al.: J. Am. Coll Cardiol., 46, 1785 (2005), Schrier, R., et al.: N. Engl. J. Med., 355, 2099 (2006),

Formel: C₂₆H₂₅ClN₂O₃

Farbe und Form: Off White Solid

Molekulargewicht: 448.94

Ref: TR-T536640

Tolvaptan

CAS: 331947-66-1

Tolvaptan is a non-peptide, small molecule activator of the vasopressin V2 receptor. It is also an inhibitor of the L-type voltage-gated calcium channel and a ligand for the G protein-coupled receptor VPAC1. Tolvaptan binds to the vasopressin V2 receptor and stimulates cAMP production in the kidney, leading to increased water reabsorption from urine. This increases blood volume and reduces blood pressure. Tolvaptan has been shown to be effective in reducing blood pressure in patients with mild hypertension.

Formel: C₂₆H₂₅ClN₂O₃

Reinheit: Min. 95%

Molekulargewicht: 448.90 g/mol

Ref: 3D-GNA94766

(R)-Tolvaptan

CAS: 331947-66-1

Formel: C₂₆H₂₅ClN₂O₃

Molekulargewicht: 448.95

Ref: ST-EA-CP-T26025