CAS 334658-24-1

Bodipy Cyclopamine (>85%)

Kontrolliertes Produkt

CAS: 334658-24-1

Stability Light Sensitive
Applications It is a fluorescent derivative of Cyclopamine that retains potency in Shh signaling inhibition (IC50=150nM).
References Chen, K.J., et al.: Genes Develop., 16, 2743 (2002)

Formel: C₄₉H₇₀BF₂N₅O₄

Farbe und Form: Neat

Molekulargewicht: 841.92

Ref: TR-B674800

Bodipy Cyclopamine-d10

Kontrolliertes Produkt

CAS: 334658-24-1

Formel: C₄₉D₁₀H₆₀BF₂N₅O₄

Farbe und Form: Neat

Molekulargewicht: 851.981

Ref: TR-B674802

BODIPY-Cyclopamine

CAS: 334658-24-1

BODIPY-Cyclopamine is a fluorescent ligand for the Smoothened (SMO) receptor. SMO activation, which is regulated by Patch protein, is linked to tumorigenesis when excessively activated. Using NanoBRET technology, sensitive detection of the resonance energy transfer between SMO and BODIPY-Cyclopamine can be achieved, facilitating high-throughput screening and kinetic analysis. Additionally, studying the binding sites of BODIPY-Cyclopamine on SMO can aid in discovering SMO-targeted drugs.

Formel: C₄₉H₇₀BF₂N₅O₄

Farbe und Form: Solid

Molekulargewicht: 841.92

Ref: TM-T88053

Bodipy cyclopamine

CAS: 334658-24-1

Fluorescent derivative of cyclopamine

Formel: C₄₉H₇₀BF₂N₅O₄

Reinheit: Min. 95%

Farbe und Form: Red Solid

Molekulargewicht: 841.92 g/mol

Ref: 3D-FB18988