CAS 37784-17-1

N-Boc-D-Prolin

Beschreibung:

N-Boc-D-Prolin, mit der CAS-Nummer 37784-17-1, ist ein Derivat der Aminosäure Prolin, das durch das Vorhandensein einer tert-butyloxycarbonyl (Boc) Schutzgruppe am Stickstoffatom gekennzeichnet ist. Diese Modifikation verbessert seine Stabilität und Löslichkeit, was es zu einem wertvollen Zwischenprodukt in der Peptidsynthese und der organischen Chemie macht. N-Boc-D-Prolin ist typischerweise ein weißes bis off-white kristallines Feststoff und ist in gängigen organischen Lösungsmitteln wie Dichlormethan und Dimethylformamid löslich, aber weniger löslich in Wasser. Die Boc-Gruppe dient als schützende Einheit, die unter sauren Bedingungen entfernt werden kann, was die selektive Deprotektion der Aminogruppe bei Bedarf ermöglicht. Diese Verbindung wird häufig in der Synthese von Peptiden und anderen bioaktiven Molekülen verwendet, da sie die Bildung von Peptidbindungen erleichtert und gleichzeitig die Chiralität des D-Prolin-Restes bewahrt. Ihre strukturellen Merkmale und Reaktivität machen sie zu einem wichtigen Baustein in der medizinischen Chemie und der Arzneimittelentwicklung.

Formel: C₁₀H₁₆NO₄

InChl: InChI=1/C10H17NO4/c1-10(2,3)15-9(14)11-6-4-5-7(11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)/p-1/t7-/m1/s1

SMILES: CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)[O-]

Synonyme:

• (2R)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylate
• 1-Boc-D-proline
• Boc-D-Pro-OH
• Boc-D-proline

N-(tert-Butoxycarbonyl)-D-proline

CAS: 37784-17-1

Formel: C₁₀H₁₇NO₄

Reinheit: >98.0%(T)(HPLC)

Farbe und Form: White to Almost white powder to crystal

Molekulargewicht: 215.25

Ref: 3B-B2977

N-Boc-D-proline, 98+%

CAS: 37784-17-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formel: C₁₀H₁₇NO₄

Reinheit: 98+%

Farbe und Form: White, Crystals or powder or crystalline powder

Molekulargewicht: 215.25

Ref: 02-L08826

Boc-D-Pro-OH

CAS: 37784-17-1

Bachem ID: 4000664.

Formel: C₁₀H₁₇NO₄

Reinheit: > 99.5%

Farbe und Form: White

Molekulargewicht: 215.25

Ref: 01-4000664

N-Boc-D-proline

CAS: 37784-17-1

Formel: C₁₀H₁₇NO₄

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 215.2463

Ref: IN-DA0035CW

N-Boc-D-proline

CAS: 37784-17-1

N-Boc-D-proline

Reinheit: 98%

Farbe und Form: White Powder

Molekulargewicht: 215.25g/mol

Ref: 54-OR307074

N-Boc-D-proline

CAS: 37784-17-1

Formel: C₁₀H₁₇NO₄

Reinheit: ≥ 98.0%

Farbe und Form: White powder or crystals

Molekulargewicht: 215.25

Ref: 7W-GM9500

Boc-D-Pro-OH

CAS: 37784-17-1

M03316 - Boc-D-Pro-OH

Formel: C₁₀H₁₇NO₄

Reinheit: 97%

Farbe und Form: Solid, Crystalline Powder or Powder

Molekulargewicht: 215.249

Ref: 10-M03316

N-Boc-D-proline

CAS: 37784-17-1

Formel: C₁₀H₁₇NO₄

Molekulargewicht: 215.25

Ref: 4Z-P-166060

tert-Butoxycarbonyl-D-proline

Kontrolliertes Produkt

CAS: 37784-17-1

Applications tert-Butoxycarbonyl-D-proline is Boc protected D-proline (P755990). It is used to prepare trichostatin A and trapoxin B analogs as histone deacetylase inhibitors. It is also used to prepare potent and selective nonpeptide inhibitors of caspases 3 and 7.
References Jung, M., et al.: Bioorg. Med. Chem. Lett., 7, 1655 (1997); Lee, D., et al.: J. Med. Chem,, 44, 2015 (2001)

Formel: C₁₀H₁₇NO₄

Farbe und Form: Neat

Molekulargewicht: 215.25

Ref: TR-B692535

N-Boc-D-proline

CAS: 37784-17-1

N-Boc-D-proline is a lipase inhibitor that is used in the preparation of quinine, aldehyde, and carboxylate. N-Boc-D-proline has been shown to inhibit the activity of the sodium channels, which may be due to its ability to bind to the termini of these channels. The inhibition of sodium channels can lead to a decrease in nerve excitability and seizures. N-Boc-D-proline was synthesized by an organocatalytic method using sodium bicarbonate as the catalyst. It was found that this compound was stereoselective with respect to its activity on different enantiomers of chiral substrates. Preparative methods for N-Boc-D-proline include column chromatography or crystallization with diethyl ether or ethyl acetate. The isolated yield is about 99%.

Formel: C₁₀H₁₇NO₄

Reinheit: Min. 95%

Farbe und Form: Powder

Molekulargewicht: 215.25 g/mol

Ref: 3D-FB11371

Boc-D-Pro-OH

CAS: 37784-17-1

Boc-D-Pro-OH is a model compound for the synthesis of peptides. Boc-D-Pro-OH has been used in many surface-enhanced Raman spectroscopy studies to investigate the stereochemistry of glycosidic bonds. It has also been used in pharmacokinetic studies to investigate the drug's absorption, distribution, metabolism, and excretion (ADME) properties. The solute is soluble in water due to its hydrophilic nature. Boc-D-Pro-OH is an enantiomer of Boc-L-Pro-OH and a functional group that contains a trifluoromethyl group. This chemical can be used in Tools for Peptide Synthesis with other compounds to form peptides with specific amino acid sequences.

Formel: C₁₀H₁₇NO₄

Reinheit: Min. 95%

Molekulargewicht: 215.25 g/mol

Ref: 3D-BDP-2610

BOC-D-Proline extrapure, 99%

CAS: 37784-17-1

Formel: C₁₀H₁₇NO₄

Reinheit: min. 99%

Farbe und Form: White, Crystalline compound

Molekulargewicht: 215.30

Ref: SR-93481