CAS 440327-45-7

3'-O-Levulinyl-2'-deoxyadenosine

CAS: 440327-45-7

Nucleoside Derivatives - 3’-Modifed nucleosides, Protected nucleosides with NH2/OH group open; Used for conjugation

Formel: C₁₅H₁₉N₅O₅

Farbe und Form: Solid

Molekulargewicht: 349.34

Ref: TM-TNU1126

3’-O-Levulinyl-2’-deoxyadenosine

CAS: 440327-45-7

3’-O-Levulinyl-2’-deoxyadenosine is a nucleoside and a prodrug for the anticancer drug 2’,3’-dideoxyadenosine. 3’-O-Levulinyl-2’-deoxyadenosine is an activator of deoxyribonucleic acid (DNA) synthesis and also inhibits DNA repair. In mammals, 3’-O-levulinyl-2’deoxyadenosine is converted to 2’,3′ dideoxyadenosine monophosphate (ddAMP), which can be phosphorylated to ddATP in cells. 3′ -O -levulinyl -2′ -deoxyadenosine has been shown to inhibit the growth of cancer cells in vitro and in vivo.

Reinheit: Min. 95%

Ref: 3D-NL163003