CAS 4548-34-9

Tranylcypromine (2-PCPA) HCl

CAS: 4548-34-9

Formel: C₉H₁₂ClN

Reinheit: 97%

Farbe und Form: Solid

Molekulargewicht: 169.6513

Ref: IN-DA00DJQF

(+)-Tranylcypromine HCl ((+)-trans-2-Phenylcyclopropylamine HCl)

CAS: 4548-34-9

Formel: C₉H₁₁N·HCl

Farbe und Form: White To Off-White Solid

Molekulargewicht: 133.19 36.46

Ref: 4Z-T-676

(1S,2R)-2-Phenylcyclopropan-1-amine hydrochloride

CAS: 4548-34-9

(1S,2R)-2-Phenylcyclopropan-1-amine hydrochloride

Reinheit: ≥95%

Farbe und Form: Solid

Molekulargewicht: 169.65g/mol

Ref: 54-OR310537

Tranylcypromine Hydrochloride

Kontrolliertes Produkt

CAS: 4548-34-9

Applications Tranylcypromine is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively.
References Zhang, W., et al.: Drug Metab. Dispos., 29, 897 (2001); Hong S., et al.: J. Biol. Chem., 255, 9538 (1980); Taavitsainen, P., et al.: Drug Metab. Dispos., 29, 217 (2001); Negishi, T., et al.: Environ. Health Perspect., 112, 1159 (2004)

Formel: C₉H₁₂ClN

Farbe und Form: Neat

Molekulargewicht: 169.65

Ref: TR-T715000

(1S,2R)-Tranylcypromine-d5 Hydrochloride

Kontrolliertes Produkt

CAS: 4548-34-9

Formel: C₉H₆D₅N•HCl

Farbe und Form: Neat

Molekulargewicht: 138.12 + (36.46)

Ref: TR-T715002

Tranylcypromine Hydrochloride (1 mg/mL in Methanol)

Kontrolliertes Produkt

CAS: 4548-34-9

Formel: C₉H₁₂ClN

Farbe und Form: Single Solution

Molekulargewicht: 169.65

Ref: TR-KIT8185

(+)-Tranylcypromine hydrochloride

Kontrolliertes Produkt

CAS: 4548-34-9

(+)-Tranylcypromine hydrochloride is a drug that is used for the treatment of depression. It inhibits monoamine oxidase (MAO) and reversibly inhibits the activity of tyrosine hydroxylase, which are enzymes involved in the production of amines. The binding of this drug to lysine residues on the enzyme MAO-A prevents the oxidation of dopamine and other neurotransmitters, such as serotonin. This drug has shown to have pluripotent effects in animal studies. (+)-Tranylcypromine hydrochloride has been shown to induce dedifferentiation in human liver cells grown in culture, which may be due to its ability to inhibit protein synthesis. There are many known drug interactions with (+)-tranylcypromine hydrochloride. Clinical studies have found that it increases cardiovascular toxicity when taken with drugs such as beta blockers, calcium channel blockers, and clonidine.

Formel: C₉H₁₁N·HCl

Reinheit: Min. 95%

Molekulargewicht: 169.65 g/mol

Ref: 3D-EAA54834

(1S,2R)-Tranylcypromine hydrochloride

CAS: 4548-34-9

(1S,2R)-Tranylcypromine hydrochloride ((1S,2R)-SKF 385), a potent antidepressant, functions by inhibiting both MAO and LSD1.

Formel: C₉H₁₂ClN

Farbe und Form: Solid

Molekulargewicht: 169.651

Ref: TM-T71826