CAS 474-25-9

Chenodesoxycholsäure

Beschreibung:

Chenodesoxycholsäure (CDCA) ist eine Gallensäure, die eine entscheidende Rolle bei der Verdauung und Absorption von Nahrungsfetten und fettlöslichen Vitaminen im Darm spielt. Es handelt sich um ein weißes bis off-white kristallines Pulver, das in Wasser und organischen Lösungsmitteln wie Ethanol und Methanol löslich ist. CDCA wird in der Leber aus Cholesterin synthetisiert und ist eine primäre Gallensäure, was bedeutet, dass sie direkt aus Cholesterin produziert wird, anstatt von anderen Gallensäuren abgeleitet zu werden. Ihre chemische Struktur weist einen Steroidkern mit Hydroxylgruppen an spezifischen Positionen auf, was zu ihrer amphipathischen Natur beiträgt, die es ihr ermöglicht, Fette zu emulgieren. CDCA ist an der Regulation des Cholesterinstoffwechsels beteiligt und wurde auf sein therapeutisches Potenzial bei Erkrankungen wie Gallensteinen und bestimmten Lebererkrankungen untersucht. Darüber hinaus kann es das Mikrobiom des Darms beeinflussen und hat Auswirkungen auf die metabolische Gesundheit. Als natürlich vorkommende Substanz wird es auch in verschiedenen pharmazeutischen Formulierungen und Nahrungsergänzungsmitteln verwendet.

Formel: C₂₄H₄₀O₄

InChl: InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1

InChI Key: InChIKey=RUDATBOHQWOJDD-BSWAIDMHSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@H]3O)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]

Synonyme:

• (3Alpha,5Beta,7Alpha,8Xi,9Xi,14Xi)-3,7-Dihydroxycholan-24-Oic Acid
• (3Alpha,5Beta,7Alpha,8Xi,9Xi,14Xi)-3,7-Dihydroxycholan-24-Oicacid
• (3α,5β,7α)-3,7 Dihydroxycholan-24-oic acid
• (5Beta)-3,7-Dihydroxycholan-24-Oic Acid
• (5Beta)-3,7-Dihydroxycholan-24-Oicacid
• 17β-(1-Methyl-3-carboxypropyl)etiocholane-3α,7α-diol
• 3-Alpha,7-Alpha-Dihydroxy-5-Beta-Cholan-24-Oicacid
• 3alpha,7alpha-Dihydroxy-5beta-cholanic acid
• 3α,7α-Dihydroxy-5β-cholan-24-oic acid
• 3α,7α-Dihydroxy-5β-cholanic acid
• 3α,7α-Dihydroxy-5β-cholanoic acid
• 3α,7α-Dihydroxycholanic acid
• 5β-Cholan-24-oic acid, 3α,7α-dihydroxy-
• 5β-Cholanic acid, 3α,7α-dihydroxy-
• 7α-Hydroxylithocholic acid
• Acide chenodesoxycholique
• Acido Chenodeoxicholico
• Anthropodeoxycholic acid
• Anthropodesoxycholic acid
• Anthropododesoxycholic acid
• CDC
• CHOLANIC ACID, 3-α, 7-α-DIHYDROXY-5-β-
• Cdca
• Chendeoxycholicacid
• Chendol
• Chenic acid
• Chenix
• Chenocedon
• Chenocol
• Chenodeoxcholic acid
• Chenodesoxycholic acid
• Chenodesoxycholsaure
• Chenodex
• Chenodiol
• Chenofalk
• Chenossil
• Cholan-24-oic acid, 3,7-dihydroxy-, (3α,5β,7α)-
• Cholanorm
• Fluibil
• Gallodesoxycholic acid
• Hekbilin
• Kebilis

Chenodeoxycholic Acid

CAS: 474-25-9

Formel: C₂₄H₄₀O₄

Reinheit: >97.0%(GC)

Farbe und Form: White to Light yellow powder to crystaline

Molekulargewicht: 392.58

Ref: 3B-C0750

Chenodeoxycholic acid

CAS: 474-25-9

Chenodeoxycholic acid

Farbe und Form: Beige

Ref: 47-926

CHENODEOXYCHOLIC ACID CRS

CAS: 474-25-9

CHENODEOXYCHOLIC ACID CRS

Formel: C₂₄H₄₀O₄

Molekulargewicht: 392.572

Ref: 41-C1050000

CHENODEOXYCHOLIC ACID FOR PEAK IDENTIFICATION CRS

CAS: 474-25-9

CHENODEOXYCHOLIC ACID FOR PEAK IDENTIFICATION CRS

Ref: 41-Y0002291

CHENODEOXYCHOLIC ACID FOR SYSTEM SUITABILITY CRS

CAS: 474-25-9

CHENODEOXYCHOLIC ACID FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0002290

Chenodeoxycholic acid

CAS: 474-25-9

Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!

Formel: C₂₄H₄₀O₄

Reinheit: 99.70% - 99.93%

Farbe und Form: White Solid

Molekulargewicht: 392.57

Ref: TM-T0847

Chenodeoxycholic Acid MaxSpec® Standard

CAS: 474-25-9

Formel: C₂₄H₄₀O₄

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 392.5720

Ref: IN-DA0039AV

Chenodeoxycholic acid, 98%

CAS: 474-25-9

Formel: C₂₄H₄₀O₄

Reinheit: ≥ 98.0%

Farbe und Form: White to off-white powder

Molekulargewicht: 392.57

Ref: 7W-GP5501

Chenodeoxycholic Acid (Ursodeoxycholic Acid EP Impurity A)

CAS: 474-25-9

Formel: C₂₄H₄₀O₄

Farbe und Form: White To Off-White Solid

Molekulargewicht: 392.58

Ref: 4Z-C-428

Chenodeoxycholic acid, 97%, from chicken

CAS: 474-25-9

Formel: C₂₄H₄₀O₄

Reinheit: ≥ 97.0%

Farbe und Form: White or off-white powder

Molekulargewicht: 392.57

Ref: 7W-GP0381

Chenodeoxycholic acid

CAS: 474-25-9

Chenodeoxycholic acid

Formel: C₂₄H₄₀O₄

Reinheit: ≥98%

Molekulargewicht: 392.57

Ref: 54-BUP16548

Chenodeoxycholic acid

CAS: 474-25-9

Formel: C₂₄H₄₀O₄

Reinheit: ≥ 98.0%

Farbe und Form: White to off-white powder

Molekulargewicht: 392.57

Ref: 7W-GP7061

Chenodeoxycholic-2,2,4,4-d4Acid

CAS: 474-25-9, 99102-69-9

Reinheit: 98 atom % D

Farbe und Form: White Solid

Molekulargewicht: 396.60

Ref: 3U-D2772

Chenodeoxycholic acid

CAS: 474-25-9

Formel: C24H40O4

Reinheit: >98%

Farbe und Form: Solid

Molekulargewicht: 392.57

Ref: 48-65-1005

Chenodeoxycholic acid

CAS: 474-25-9

Formel: C₂₄H₄₀O₄

Reinheit: 95%~99%

Farbe und Form: Cryst.

Molekulargewicht: 392.58

Ref: BP-SBP03907

Chenodeoxycholic acid (Standard)

CAS: 474-25-9

Chenodeoxycholic acid (Standard) is an analytical reference standard intended for research and quantitative applications, representing a hydrophobic primary bile acid that activates nuclear farnesoid X receptor signaling pathways involved in cholesterol homeostasis, bile acid metabolism, and lipid regulation, and is widely used for biochemical validation, metabolic studies, and analytical method development.

Formel: C₂₄H₄₀O₄

Molekulargewicht: 392.57

Ref: TM-TMSM-1459

Chenodeoxycholic acid

CAS: 474-25-9

Reinheit: 95.0%

Farbe und Form: Solid, Crystalline Powder or Needles or Powder

Molekulargewicht: 392.5799865722656

Ref: 10-F218990

Chenodeoxycholic acid

CAS: 474-25-9

Chenodeoxycholic acid

Formel: C₂₄H₄₀O₄

Reinheit: Loss on drying: 0.3%. (Typical Value in Batch COA)

Farbe und Form: White Solid-Powder

Molekulargewicht: 392.57199

Ref: 54-BIB6026

Chenodeoxycholic Acid

CAS: 474-25-9

Formel: C₂₄H₄₀O₄

Molekulargewicht: 392.58

Ref: ST-EA-CP-C93000

Ursodeoxycholic Acid EP Impurity A

CAS: 474-25-9

Formel: C₂₄H₄₀O₄

Molekulargewicht: 392.57

Ref: ST-EA-CP-U1001

Chenodeoxycholic Acid

Kontrolliertes Produkt

CAS: 474-25-9

Impurity Ursodeoxycholic Acid EP Impurity A
Applications Chenodeoxycholic Acid (Ursodeoxycholic Acid EP Impurity A) is a major bile acid in many vertebrates, occurring as the N-glycine and/or N-taurine conjugate. With other bile acids, forms mixed micelles with lecithin in bile which solubilize cholesterol and thus facilitates its excretion. Facilitates fat absorption in the small intestine by micellar solubilization of fatty acids and monoglycerides. Anticholelithogenic. Epimeric with Ursodiol.
References Danzinger, et al.: N. Engl. J. Med., 286, 1 (1972), Iser, J.H., et al.: Drugs, 21, 90 (1981), Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986),

Formel: C₂₄H₄₀O₄

Farbe und Form: Neat

Molekulargewicht: 392.57

Ref: TR-C291900

Chenodeoxycholic acid

Kontrolliertes Produkt

CAS: 474-25-9

Chenodeoxycholic acid is a human primary bile acid which is also found the bile of geese. Its C-7 epimer, Ursodeoxycholic acid is found in bear’s bile. Both bile acids are used for the treatment of gallstones, although Ursodeoxycholic acid has shown superior efficacy (bear’s bile extracts are also used in Chinese medicine).

Formel: C₂₄H₄₀O₄

Reinheit: Min. 95 Area-%

Farbe und Form: White Powder

Molekulargewicht: 392.57 g/mol

Ref: 3D-FC09675

Chenodeoxycholic Acid-[d9] in Methanol

CAS: 474-25-9

Methanol

Ref: BE-MD-1004D9XM-100

Chenodeoxycholic Acid-[13C3] in Methanol

CAS: 474-25-9

Methanol

Ref: BE-MC-1004XM-100

Chenodeoxycholic Acid in Methanol

CAS: 474-25-9

Methanol

Ref: BE-MU-1004YM-1000

Chenodeoxycholic acid

CAS: 474-25-9

(R)-4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Formel: C₂₄H₄₀O₄

Reinheit: 98+%

Molekulargewicht: 392.57

Ref: IN-DG764669

Chenodeoxycholic Acid-d7 (Major)

Kontrolliertes Produkt

CAS: 474-25-9

Applications Chenodeoxycholic Acid-d7 is a labelled analogue of Chenodeoxycholic Acid (C291900), which is a major bile acid in many vertebrates, occurring as the N-glycine and/or N-taurine conjugate. With other bile acids, forms mixed micelles with lecithin in bile which solubilize cholesterol and thus facilitates its excretion. Fcilitates fat absorption in the small intestine by micellar solubilization of fatty acids and monoglycerides. Anticholelithogenic. Epimeric with Ursodiol. In addition, Chenodeoxycholic Acid-d7 is an intermediate in synthesizing Glycochenodeoxycholic Acid-d7 Sodium Salt (G641257), which is a labelled Glycochenodeoxycholic Acid (G641255). A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for
References Danzinger, et al.: N. Engl. J. Med., 286, 1 (1972); Iser, J.H., et al.: Drugs, 21, 90 (1981); Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986); Ollila, F., et al.: Langmuir, 17, 7107 (2001); Uekama, K., et al.: Chem. Pharm. Bull., 52, 900 (2004); Tongiani, S., et al.: J. Pharm. Sci., 94, 2380 (2005)

Formel: C₂₄H₃₃D₇O₄

Farbe und Form: Neat

Molekulargewicht: 399.62

Ref: TR-C291904

Chenodeoxycholic acid

Kontrolliertes Produkt

CAS: 474-25-9

Chenodeoxycholic acid is a human primary bile acid which is also found the bile of geese. Its C-7 epimer, Ursodeoxycholic acid is found in bear’s bile. Both bile acids are used for the treatment of gallstones, although Ursodeoxycholic acid has shown superior efficacy (bear’s bile extracts are also used in Chinese medicine).

Formel: C₂₄H₄₀O₄

Reinheit: Min. 98 Area-%

Molekulargewicht: 392.58 g/mol

Ref: 3D-C-2900