CAS 502632-66-8

PX-866

CAS: 502632-66-8

PX-866

Formel: C₂₉H₃₅NO₈

Reinheit: By hplc: 98.35% (Typical Value in Batch COA)

Farbe und Form: orange powder

Molekulargewicht: 525.59g/mol

Ref: 54-BIP1009

PX 866

CAS: 502632-66-8

Potent and irreversible inhibitor of phosphoinositide-3-kinase (PtdIns-3-kinase) with IC50 of 0.1 nM. PX 866 inhibited cell motility and growth of 3D spheroids of glioblastoma, breast, prostate and colon cancer cell lines at low nanomolar concentrations. PX 866 also exhibited anti-tumoral activity in vivo in xenograft models for ovarian and lung cancer.

Formel: C₂₉H₃₅NO₈

Reinheit: Min. 98 Area-%

Farbe und Form: Powder

Molekulargewicht: 525.59 g/mol

Ref: 3D-BP162743

Sonolisib

CAS: 502632-66-8

Sonolisib is an irreversible and pan-isoform inhibitor of PI3K (IC50=0.1 nM (p110α), 1.0 nM (p120γ), 2.9 nM (p110δ)).

Formel: C₂₉H₃₅NO₈

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 525.59

Ref: TM-T16908