CAS 504435-15-8

11,12-epoxy-5(Z),8(Z),14(Z),17(Z)- eicosatetraenoic acid

CAS: 504435-15-8

Formel: C20H30O3

Reinheit: >98%

Farbe und Form: In solution, Ethanol

Molekulargewicht: 318.45

Ref: 48-12-2041

(±)11(12)-EpETE

CAS: 504435-15-8

Eicosapentaenoic acid (EPA) is metabolized into epoxyeicosatetraenoic acids (EpETE) by multiple cytochrome P450 isoforms. The predominant compound of this epoxygenase pathway, (±)17(18)-EpETE, induces relaxation in vascular and airway smooth muscles through its action on large conductance Ca2+-activated K+ (BKCa) channels, specifically by binding to the BKα channel subunits. Another notable epoxygenase pathway derivative, (±)11(12)-EpETE, also generated from EPA via CYP450 activity in both in vitro and in vivo studies, has biological and physiological roles that are yet to be fully elucidated.

Formel: C₂₀H₃₀O₃

Farbe und Form: Solid

Molekulargewicht: 318.5

Ref: TM-T84501