CAS 51-35-4

L-Hydroxyprolin

Beschreibung:

L-Hydroxyprolin ist eine nicht-proteinogene Aminosäure, die ein Derivat von Prolin ist und durch das Vorhandensein einer Hydroxylgruppe im Pyrrolidinring gekennzeichnet ist. Sie kommt häufig in Kollagen vor und spielt eine entscheidende Rolle bei der Stabilisierung der dreifachen Helixstruktur dieses Proteins, die für die Integrität des Bindegewebes unerlässlich ist. L-Hydroxyprolin ist ein weißes kristallines Feststoff, der in Wasser löslich ist und aufgrund der Anwesenheit der Carboxylgruppe eine leicht saure Natur hat. Seine chemische Formel ist C5H9NO3 und hat ein Molekulargewicht von etwa 131,13 g/mol. Diese Aminosäure ist wichtig für verschiedene biochemische Prozesse, einschließlich der Kollagensynthese und des Stoffwechsels. Darüber hinaus wird L-Hydroxyprolin in der Forschung und in pharmazeutischen Anwendungen eingesetzt, insbesondere in Studien zu Fibrose und Wundheilung. Seine einzigartigen strukturellen Eigenschaften und biologische Bedeutung machen es zu einer wertvollen Verbindung in wissenschaftlichen und medizinischen Bereichen.

Formel: C₅H₉NO₃

InChl: InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1

InChI Key: InChIKey=PMMYEEVYMWASQN-DMTCNVIQSA-N

SMILES: C(O)(=O)[C@@H]1C[C@@H](O)CN1

Synonyme:

• (-)-4-Hydroxy-2-pyrrolidinecarboxylic acid
• (2S,4R)-(-)-4-Hydroxy-2-pyrrolinecarboxylic acid
• (2S,4R)-(-)-4-Hydroxypyrrolidine-2-carboxylic acid
• (2S,4R)-4-Hydroxyproline
• (4R)-4-Hydroxy-<span class="text-smallcaps">L</span>-proline
• (4R)-4-hydroxy-L-proline
• (4R,2S)-Hydroxyproline
• (R)-4-Hydroxy-(S)-proline
• (R)-4-Hydroxy-<span class="text-smallcaps">L</span>-proline
• (R)-4-Hydroxy-L-proline
• (S)-Hydroxyproline
• 1-Hydroxyproline
• 1-hydroxy-L-proline
• 3-hydroxy-L-proline
• 4(R)-Hydroxy-2(S)-pyrrolidinecarboxylic acid
• 4(R)-Hydroxyproline
• 4-Hydroxy-(S)-proline
• 4-Hydroxy-<span class="text-smallcaps">L</span>-proline
• 4-Hydroxy-L-proline
• 4-Hydroxyproline
• 4-L-Hydroxyproline
• 4-hydroxy-L-proline (trans)
• 4-trans-Hydroxy-<span class="text-smallcaps">L</span>-proline
• 4-trans-Hydroxy-L-proline
• <span class="text-smallcaps">L</span>-4-Hydroxyproline
• <span class="text-smallcaps">L</span>-Hydroxyproline
• <span class="text-smallcaps">L</span>-Hypro
• <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, (4R)-
• <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, trans-
• <span class="text-smallcaps">L</span>-trans-4-Hydroxyproline
• H-Hyp-OH
• Hydroxy-<span class="text-smallcaps">L</span>-proline
• Hydroxy-L-proline
• Hydroxyproline
• Hydroxyproline, L-
• Hypro
• L-4-Hydroxyprolin
• L-4-Hydroxyproline
• L-4-hidroxiprolina
• L-Hydroxyproline
• L-Hypro
• L-Proline, 4-hydroxy-, (4R)-
• L-Proline, 4-hydroxy-, trans-
• L-trans-4-Hydroxyproline
• L_s-Hydroxyproline
• Ls-Hydroxyproline
• Nsc 46704
• Proline, 4-hydroxy-
• Proline, 4-hydroxy-, <span class="text-smallcaps">L</span>-
• Proline, 4-hydroxy-, L-
• Trans-4-hydroxyl-L-proline
• delta-Hydroxyproline
• trans-(2S,4R)-4-Hydroxy-<span class="text-smallcaps">L</span>-proline
• trans-4-Hydroxy-<span class="text-smallcaps">L</span>-proline
• trans-4-Hydroxyproline
• trans-<span class="text-smallcaps">L</span>-4-Hydroxyproline
• trans-<span class="text-smallcaps">L</span>-Hydroxyproline
• trans-L-4-Hydroxyproline
• trans-L-Hydroxyproline

trans-4-Hydroxy-L-proline

CAS: 51-35-4

Formel: C₅H₉NO₃

Reinheit: >99.0%(T)(HPLC)

Farbe und Form: White powder to crystaline

Molekulargewicht: 131.13

Ref: 3B-H0296

trans-4-Hydroxy-L-proline, 99+%

CAS: 51-35-4

trans-4-Hydroxy-L-proline is used as a reagent for the preparation of neuroexcitatory kainoids and antifungal echinocandins. It is also involved in the synthesis of chiral ligands for enantioselective ethylation of aldehydes. This Thermo Scientific Chemicals brand product was originally part of the

Formel: C₅H₉NO₃

Reinheit: 99+%

Farbe und Form: White to pale cream, Crystals or powder or crystalline powder

Molekulargewicht: 131.13

Ref: 02-A11851

H-Hyp-OH

CAS: 51-35-4

Kristensen et al. achieved the selective O-acylation of unprotected trans-hydroxyproline.

Formel: C₅H₉NO₃

Farbe und Form: White

Molekulargewicht: 131.13

Ref: 01-4002357

L-4-Hydroxyproline

CAS: 51-35-4

Formel: C₅H₉NO₃

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 131.1299

Ref: IN-DA0035PX

L-Hydroxyproline

CAS: 51-35-4

L-Hydroxyproline

Reinheit: ≥98%

Molekulargewicht: 131.13g/mol

Ref: 54-BUP18166

trans-4-Hydroxy-L-proline, GlenCell™, suitable for cell culture

CAS: 51-35-4

Formel: C₅H₉NO₃

Reinheit: (dried basis) 99.0 - 101.0 %

Farbe und Form: White crystalline powder

Molekulargewicht: 131.13

Ref: 7W-GM0902

trans-4-Hydroxy-L-Proline

CAS: 51-35-4

Formel: C₅H₉NO₃

Farbe und Form: White To Off-White Solid

Molekulargewicht: 131.13

Ref: 4Z-P-166019

(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid

CAS: 51-35-4

(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid

Formel: C₅H₉NO₃

Reinheit: ≥95%

Farbe und Form: white crystals

Molekulargewicht: 131.12985g/mol

Ref: 54-OR6733

trans-4-Hydroxy-L-proline

CAS: 51-35-4

Formel: C₅H₉NO₃

Reinheit: 98.5 - 101.5 %

Farbe und Form: White to off-white crystalline powder, or colourless crystals

Molekulargewicht: 131.13

Ref: 7W-GM7180

L-Hydroxyproline

CAS: 51-35-4

Formel: C₅H₉NO₃

Reinheit: 95%~99%

Molekulargewicht: 131.131

Ref: BP-BP3523

L-Hydroxyproline

CAS: 51-35-4

L-Hydroxyproline (L-Hydroxyprolin) is one of the hydroxyproline (Hyp) isomers.

Formel: C₅H₉NO₃

Reinheit: 99.77% - 99.92%

Farbe und Form: Solid

Molekulargewicht: 131.13

Ref: TM-T2A2476

trans-4-Hydroxy-L-proline

Kontrolliertes Produkt

CAS: 51-35-4

Applications A natural constituent of animal structural proteins such as collagen and elastin. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.
References Langmaier, F. et al.: Int. J. Cosm. Sci., 24, 273 (2002); Lawrence, C., et al.: Biochem. J., 313, 185 (1996); Mori, H., et al.: J. Bacteriol.; 179, 5677 (1997); Clifton, I., et al.: Eur. J. Biochem., 268, 6625 (2001);

Formel: C₅H₉NO₃

Farbe und Form: Neat

Molekulargewicht: 131.13

Ref: TR-H952376

trans-4-Hydroxy-L-proline

CAS: 51-35-4

Proline is a non-essential amino acid that is found in the basic structure of collagen. Proline has been shown to have physiological effects, including a protective effect on the myocardium, and can be used as an analytical method for detecting proline residues in biological samples. Trans-4-Hydroxy-L-proline is a proline derivative that has been shown to inhibit collagenase activity in vitro. It was also shown to have an optimum concentration of 1 mM and a matrix effect at pH 6.5. The model system used to study trans-4-hydroxy-l-proline was the enzyme extracted from rat liver.

Formel: C₅H₉NO₃

Farbe und Form: White Powder

Molekulargewicht: 131.13 g/mol

Ref: 3D-FH14370

H-Hyp-OH

CAS: 51-35-4

M03214 - H-Hyp-OH

Formel: C₅H₉NO₃

Reinheit: 97%

Farbe und Form: Off-white crystalline powder

Molekulargewicht: 131.131

Ref: 10-M03214

L-Hydroxyproline extrapure CHR, 99%

CAS: 51-35-4

Formel: C₅H₉NO₃

Reinheit: min. 99.0%

Farbe und Form: White to off white, Crystalline powder, Clear, Colourless to Pale yellow

Molekulargewicht: 131.13

Ref: SR-26921

trans-4-Hydroxy-L-proline-d6

Kontrolliertes Produkt

CAS: 51-35-4

Formel: C₅D₆H₃NO₃

Farbe und Form: Neat

Molekulargewicht: 137.167

Ref: TR-H952374