CAS 552-16-9

2-Nitrobenzoesäure

Beschreibung:

2-Nitrobenzoesäure ist eine aromatische Carbonsäure, die durch das Vorhandensein einer Nitrogruppe (-NO2) und einer Carboxylgruppe (-COOH), die an einen Benzolring gebunden sind, gekennzeichnet ist. Ihre chemische Formel lautet C7H5NO4, und sie weist eine Nitrogruppe auf, die in ortho-Position zur Carboxylgruppe positioniert ist. Diese Verbindung erscheint typischerweise als gelbes kristallines Feststoff und ist bekannt für ihre mäßige Löslichkeit in Wasser, mit besserer Löslichkeit in organischen Lösungsmitteln wie Ethanol und Aceton. 2-Nitrobenzoesäure wird in verschiedenen chemischen Synthesen verwendet, einschließlich der Herstellung von Farbstoffen, Arzneimitteln und anderen organischen Verbindungen. Sie zeigt saure Eigenschaften, die es ihr ermöglichen, an Säure-Base-Reaktionen teilzunehmen. Darüber hinaus kann sie aufgrund der elektronenanziehenden Natur der Nitrogruppe elektrophile Substitutionsreaktionen durchlaufen, was die Reaktivität des aromatischen Rings beeinflusst. Sicherheitsvorkehrungen sollten beim Umgang mit dieser Verbindung getroffen werden, da sie gesundheitliche Risiken darstellen kann, wenn sie eingenommen oder eingeatmet wird.

Formel: C₇H₅NO₄

InChl: InChI=1S/C7H5NO4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4H,(H,9,10)

InChI Key: InChIKey=SLAMLWHELXOEJZ-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(N(=O)=O)C=CC=C1

Synonyme:

• 2-Nitrobenzoesaure
• 2-Nitrobenzoic Acid
• Acide 2-nitrobenzoique
• Acido 2-Nitrobenzoico
• Benzoic acid, o-nitro-
• Nsc 9576
• o-Carboxynitrobenzene
• o-Nitrobenzoic acid
• Benzoic acid, 2-nitro-

2-Nitrobenzoic Acid

CAS: 552-16-9

Formel: C₇H₅NO₄

Reinheit: >95.0%(GC)

Farbe und Form: White to Yellow to Orange powder to crystal

Molekulargewicht: 167.12

Ref: 3B-N0155

2-Nitrobenzoic acid, 95%

CAS: 552-16-9

It is employed as a synthetic reagent and can function as a growth supplement for Pseudomonas fluorescens strain KU-7. It also finds its use as a reagent for protection of amine groups and in organic synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar prod

Formel: C₇H₅NO₄

Reinheit: 95%

Farbe und Form: White to cream or pale yellow, Crystals or powder or crystalline powder

Molekulargewicht: 167.12

Ref: 02-A10393

2-Nitrobenzoic Acid

CAS: 552-16-9

Formel: C₇H₅NO₄

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 167.1189

Ref: IN-DA003HSG

2-Nitrobenzoic acid

CAS: 552-16-9

2-Nitrobenzoic acid

Reinheit: ≥98%

Molekulargewicht: 167.12g/mol

Ref: 54-BUP18320

2-Nitrobenzoic acid

CAS: 552-16-9

2-Nitrobenzoic acid

Reinheit: 99%

Molekulargewicht: 167.12g/mol

Ref: 54-OR79866

2-Nitrobenzoic acid

CAS: 552-16-9

2-Nitrobenzoic acid is an anti-growth agent with an IC50 of 8.3 μM against Jurkat cells with T-type Ca²⁺ channel alpha 1H/delta 25.

Formel: C₇H₅NO₄

Reinheit: 99.97%

Farbe und Form: Soild

Molekulargewicht: 167.12

Ref: TM-T64387

2-Nitrobenzoic acid

CAS: 552-16-9

Formel: C₇H₅NO₄

Farbe und Form: Neat

Molekulargewicht: 167.12

Ref: 04-C15557400

2-Nitrobenzoic acid - Technical

CAS: 552-16-9

2-Nitrobenzoic acid is an organic compound that is used as a reagent in the preparation of aldehydes, esters, and amides. It has been shown to be a potent inhibitor of the MCL-1 protein. This protein is an important regulator of mitochondrial permeability transition pore (MPTP) opening and apoptosis induction. The inhibition of the MPTP by 2-nitrobenzoic acid may be due to its ability to react with nitric oxide (NO) to form peroxynitrite, which reacts with MPTP proteins in the mitochondria. The use of 2-nitrobenzoic acid has been found to be effective in treating infectious diseases such as HIV, as well as autoimmune diseases such as psoriasis.

Formel: C₇H₅NO₄

Reinheit: Min. 95%

Farbe und Form: Powder

Molekulargewicht: 167.12 g/mol

Ref: 3D-FN172456

2-Nitrobenzoic acid

CAS: 552-16-9

2-Nitrobenzoic acid is a diagnostic chemical that has been used for the detection of epidermal growth factor. It also has therapeutic properties, and has been used to treat infectious diseases and autoimmune diseases. 2-Nitrobenzoic acid is an organic compound that contains two nitro groups, which are connected to a benzene ring by two carbon chains. The molecule also contains two aldehyde groups, which are connected to the benzene ring by one carbon chain each. 2-Nitrobenzoic acid is a white crystalline solid with a melting point of 118°C and boiling point of 310°C. It is soluble in water and alcohols, but insoluble in ethers or chloroform.
2-Nitrobenzoic acid can be synthesized from nitric acid and benzoic acid. This reaction produces enough heat to ignite the mixture if it's not cooled down first.

Formel: C₇H₅NO₄

Reinheit: Min. 94 Area-%

Farbe und Form: Powder

Molekulargewicht: 167.12 g/mol

Ref: 3D-FN38281

o-Nitrobenzoic acid pure, 95%

CAS: 552-16-9

Formel: C₇H₅NO₄

Reinheit: min. 95%

Farbe und Form: White to Yellow to Faint beige to Faint brown, Powder, Clear, Colourless to Yellow to Faint beige to Faint brown

Molekulargewicht: 167.12

Ref: SR-16148

2-Nitrobenzoic acid

CAS: 552-16-9

Formel: C₇H₅NO₄

Reinheit: 95%

Farbe und Form: Solid, Crystalline

Molekulargewicht: 167.12

Ref: 10-F079133

2-Nitrobenzoic Acid

Kontrolliertes Produkt

CAS: 552-16-9

Applications 2-Nitrobenzoic Acid is used as a reagent in the synthesis of several organic compounds including that of novel triazoles and a tetrazole of escitalopram which act as cholinesterase inhibitors. It is also used in the one pot synthesis of 1,4-disubstituted 1,2,3-triazoles.
References Mehr, N., et al.: Bioorg. Med. Chem., 23, 6014 (2015); Zhao, F., et al.: Chinese Chem. Lett., 27, 109 (2016);

Formel: C₇H₅NO₄

Farbe und Form: Neat

Molekulargewicht: 167.12

Ref: TR-N493515