CAS 58569-55-4

(5-Methionin)Enkephalin

Beschreibung:

(5-Methionin)Enkephalin, auch bekannt als Met-Enkephalin, ist ein Pentapeptid, das eine bedeutende Rolle bei der Schmerzmodulation und der Stressreaktion des Körpers spielt. Es besteht aus fünf Aminosäuren, nämlich Tyrosin, Glycin, Phenylalanin, Leucin und Methionin, wobei Methionin die fünfte Aminosäure am C-Terminus ist. Dieses Peptid ist ein endogenes Opioid, was bedeutet, dass es natürlich im Körper produziert wird und an Opioidrezeptoren bindet, insbesondere an den Delta-Opioidrezeptor, um analgetische Wirkungen zu erzielen. Met-Enkephalin ist an verschiedenen physiologischen Prozessen beteiligt, einschließlich Schmerzlinderung, Stimmungsregulation und der Modulation immunologischer Reaktionen. Es ist in Wasser löslich und zeigt Stabilität unter physiologischen Bedingungen, obwohl es anfällig für enzymatische Zersetzung sein kann. Die CAS-Nummer 58569-55-4 identifiziert diese Verbindung eindeutig in chemischen Datenbanken und erleichtert die Forschung und Anwendung in der Pharmakologie und Biochemie. Seine Untersuchung hat Auswirkungen auf die Entwicklung von Schmerztherapien und das Verständnis der Mechanismen von Sucht und Stimmungsstörungen.

Formel: C₂₇H₃₅N₅O₇S

InChl: InChI=1/C27H35N5O7S/c1-40-12-11-21(27(38)39)32-26(37)22(14-17-5-3-2-4-6-17)31-24(35)16-29-23(34)15-30-25(36)20(28)13-18-7-9-19(33)10-8-18/h2-10,20-22,33H,11-16,28H2,1H3,(H,29,34)(H,30,36)(H,31,35)(H,32,37)(H,38,39)/t20-,21-,22-/m0/s1

Synonyme:

• 10: PN: WO2008008805 SEQID: 10 unclaimed protein
• 153: PN: US20030176421 PAGE: 54-55 claimed protein
• 16: PN: EP1498113 PAGE: 14 claimed protein
• 25: PN: WO2005095443 SEQID: 25 claimed protein
• 3: PN: WO2008052043 SEQID: 2 claimed protein
• 46: PN: US6017496 PAGE: 120 claimed protein
• 5-L-Methionine-enkephalin
• 5-Methionine enkephalin
• Adrenorphin (human), 6-de-L-arginine-7-de-L-arginine-8-de-L-valinamide-
• Enkephalin, methionine
• Human β-endorphin(1-5)
• L-Methionine-enkephalin
• Lupex
• Met5-enkephalin
• Metenkefalin
• Met-enkephalin
• Methionine enkephalin
• Methionyl-enkephalin
• N-[N-[N-(N-L-tirosilglicil)glicil]-L-fenilalanil]-L-metionina
• N-[N-[N-(N-L-Tyrosylglycyl)glycyl]-L-phenylalanyl]-L-methionin
• N-[N-[N-(N-L-tyrosylglycyl)glycyl]-L-phenylalanyl]-L-methionine
• Nsc 374896
• Opioid growth factor
• Peptid-M
• PN: US5961923 PAGE: 135 claimed protein
• Porcine β-endorphin 1-5
• Tyr-Gly-Gly-Phe-Met-OH
• β-Endorphin(1-5)
• L-tyrosylglycylglycyl-L-phenylalanyl-L-methionine
• methionine enkephalin acetate
• H-Tyr-Gly-Gly-Phe-Met-OH
• tyrosylglycylglycylphenylalanylmethionine

Met-Enkephalin

CAS: 58569-55-4

Opioid growth factor (OGF) and its receptor form a biological axis that tonically regulates cell proliferation by delaying the G1/S interface of the cell cycle under homeostatic conditions or in neoplasia. Exogenous OGF represses growth of human pancreatic cancer cells in culture and in nude mice. OGF therapy alone or in combination with standard chemotherapies results in enhanced inhibition of DNA synthesis and tumor growth.

Formel: C₂₇H₃₅N₅O₇S

Reinheit: 99.8%

Farbe und Form: White

Molekulargewicht: 573.67

Ref: 01-4000010

H-TYR-GLY-GLY-PHE-MET-OH

CAS: 58569-55-4

Formel: C₂₇H₃₅N₅O₇S

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 573.6611

Ref: IN-DA00E8Q0

Tyr-Gly-Gly-Phe-Met-OH

CAS: 58569-55-4

Tyr-Gly-Gly-Phe-Met-OH

Reinheit: ≥95%

Molekulargewicht: 573.66g/mol

Ref: 54-BUP11145

Met-Enkephaline

CAS: 58569-55-4

Formel: C₂₇H₃₅N₅O₇S

Reinheit: 95%~99%

Farbe und Form: White to Off-white Powder

Molekulargewicht: 573.661

Ref: BP-BPPG049

Tyr-Gly-Gly-Phe-Met-OH

CAS: 58569-55-4

Tyr-Gly-Gly-Phe-Met-OH (Met-Enkephalin), is a naturally occurring, endogenous opioid peptide that inhibits tumor growth via binding to the opioid receptor.

Formel: C₂₇H₃₅N₅O₇S

Reinheit: ≥95%

Farbe und Form: White Lyophilised Solid

Molekulargewicht: 573.66

Ref: TM-T7211

Met-enkephalin

CAS: 58569-55-4

Stability Unstable in alkaline solution
Applications Met-enkephalin is an endogenous opioid peptide that increases expression levels of δ, μ and κ-opioid receptors, inhibits growth, apoptosis and proliferation in human melanoma A375 cells. Antitumor effect via regulating dendritic cells. Regulation of the immune system, therapy effects of antitumor, autoimmune diseases, AIDS, and other immune-related diseases.
References Wang, D., et al.: Mol. Med. Rep., 14, 5521 (2016); Feng, P., et al.: Weishengwuxue Zazhi, 35, 100 (2015); Meng, Y., et al.: Int. Immunopharmacol., 44, 61 (2017)

Formel: C₂₇H₃₅N₅O₇S

Farbe und Form: Neat

Molekulargewicht: 573.66

Ref: TR-M225485

Methionine-Enkephalin (Human, Porcine, Bovine, Rat, Mouse)

CAS: 58569-55-4

Methionine-Enkephalin is a peptide that is derived from the amino acid methionine. It has been shown to act on ion channels and the receptor, as well as having a number of other biological effects. Methionine-Enkephalin can be used in research for pharmacology and protein interactions. This product is an antibody against methionine-enkephalin. It can be used for cell biology and immunology research, as it recognizes the peptide sequence of methionine-enkephalin. This antibody can also be used to inhibit the activity of this peptide.

Formel: C₂₇H₃₅N₅O₇S

Reinheit: Min. 95%

Molekulargewicht: 573.66 g/mol

Ref: 3D-PEK-4042-V

Methionine-Enkephalin (Human, Porcine, Bovine, Rat, Mouse)

CAS: 58569-55-4

Methionine-Enkephalin (ME) is a peptide that has been shown to bind to the opioid receptor and inhibit the production of pro-inflammatory cytokines. ME has been shown to have an inhibitory effect on human liver cells, as well as on cultured human epidermal cells. ME may also have a role in epidermal growth factor receptors, which could be related to its anti-inflammatory effects.

Formel: C₂₇H₃₅N₅O₇S•H₂O

Reinheit: Min. 95%

Molekulargewicht: 591.68 g/mol

Ref: 3D-PEK-4042