CAS 59401-28-4

Alpha(1)-Paarungsfaktor von Saccharomyces cerevisiae

Beschreibung:

Der Alpha(1)-Paarungsfaktor, auch bekannt als Alpha-Faktor, ist ein peptidisches Pheromon, das von der Hefe Saccharomyces cerevisiae produziert wird, insbesondere von Alpha-Paarungstypzellen. Dieses Signalmolekül spielt eine entscheidende Rolle im Paarungsprozess der Hefe, indem es die Kommunikation zwischen verschiedenen Paarungstypen (Alpha und a) erleichtert. Die Struktur des Alpha-Faktors besteht aus einer kurzen Kette von Aminosäuren, die typischerweise etwa 12 Reste umfasst und eine einzigartige zyklische Struktur enthält, die seine Stabilität und biologische Aktivität erhöht. Das Pheromon bindet an spezifische Rezeptoren auf a-Zellen und löst eine Kaskade zellulärer Reaktionen aus, die zur Paarung und Fusion der beiden Zelltypen führen. Der Alpha-Faktor wird auch in verschiedenen biotechnologischen Anwendungen eingesetzt, einschließlich der Hefegenetik und Fermentationsprozesse. Seine CAS-Nummer, 59401-28-4, identifiziert ihn in chemischen Datenbanken und unterstützt die Forschung und Entwicklung. Insgesamt ist der Alpha(1)-Paarungsfaktor entscheidend für den Fortpflanzungszyklus der Hefe und dient als Modell zur Untersuchung der zellulären Signalgebung und Kommunikation in eukaryotischen Organismen.

Formel: C₈₂H₁₁₄N₂₀O₁₇S

InChl: InChI=1/C82H114N20O17S/c1-45(2)34-61(98-76(112)63(38-49-41-89-56-17-9-7-15-53(49)56)99-77(113)64(39-50-42-87-44-91-50)96-71(107)54(84)37-48-40-88-55-16-8-6-14-52(48)55)74(110)93-57(25-27-68(85)104)72(108)97-62(35-46(3)4)75(111)95-59(18-10-11-30-83)80(116)101-31-12-19-66(101)78(114)90-43-70(106)92-60(26-28-69(86)105)81(117)102-32-13-20-67(102)79(115)94-58(29-33-120-5)73(109)100-65(82(118)119)36-47-21-23-51(103)24-22-47/h6-9,14-17,21-24,40-42,44-46,54,57-67,88-89,103H,10-13,18-20,25-39,43,83-84H2,1-5H3,(H2,85,104)(H2,86,105)(H,87,91)(H,90,114)(H,92,106)(H,93,110)(H,94,115)(H,95,111)(H,96,107)(H,97,108)(H,98,112)(H,99,113)(H,100,109)(H,118,119)/t54-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-/m0/s1

SMILES: CC(C)C[C@@H](C(=N[C@@H](CCC(=N)O)C(=N[C@@H](CC(C)C)C(=N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=NCC(=N[C@@H](CCC(=N)O)C(=O)N1CCC[C@H]1C(=N[C@@H](CCSC)C(=N[C@@H](Cc1ccc(cc1)O)C(=O)O)O)O)O)O)O)O)O)N=C([C@H](Cc1c[nH]c2ccccc12)N=C([C@H](Cc1cnc[nH]1)N=C([C@H](Cc1c[nH]c2ccccc12)N)O)O)O

Synonyme:

• H-Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr-OH
• Mating Factor .alpha.
• a-Mating Factor, Yeast
• alpha1-Mating factor Saccharomyces cerevisiae
• L-tryptophyl-L-histidyl-L-tryptophyl-L-leucyl-L-glutaminyl-L-leucyl-L-lysyl-L-prolylglycyl-L-glutaminyl-L-prolyl-L-methionyl-L-tyrosine
• Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr

α-Mating Factor, yeast

CAS: 59401-28-4

alpha-Mating Factor, yeast

Formel: C₈₂H₁₁₄N₂₀O₁₇S

Molekulargewicht: 1684.2

Ref: 02-J66502

Mating Factor α

CAS: 59401-28-4

Mating pheromone of mating type α cells of S. cerevisiae. This factor inhibits DNA synthesis, thereby preventing cell division of mating type a cells. The hydrophobic peptide binds to a class D G-protein-coupled receptor Ste2p.

Formel: C₈₂H₁₁₄N₂₀O₁₇S

Reinheit: 98.4%

Farbe und Form: White Powder

Molekulargewicht: 1684.01

Ref: 01-4003514

L-Tryptophyl-L-histidyl-L-tryptophyl-L-leucyl-L-glutaminyl-L-leucyl-L-lysyl-L-prolylglycyl-L-glutaminyl-L-prolyl-L-methionyl-L-tyrosine

CAS: 59401-28-4

Formel: C₈₂H₁₁₄N₂₀O₁₇S

Reinheit: 98%

Molekulargewicht: 1683.9714

Ref: IN-DA01EO0Y

α-Factor Mating Pheromone, yeast

CAS: 59401-28-4

Alpha factor mating pheromone is a peptide of 13 amino acids secreted by Saccharomyces cerevisiae α cells.

Formel: C₈₂H₁₁₄N₂₀O₁₇S

Reinheit: 98%

Farbe und Form: White Powder

Molekulargewicht: 1684

Ref: TM-TP1106

Alpha-Mating Factor

CAS: 59401-28-4

Alpha-Mating Factor is a peptide that belongs to the group of ligands. It has been shown to bind to the androgen receptor with high affinity and act as an activator for this receptor. Alpha-Mating Factor is also able to bind to the beta-adrenergic receptor. This protein has been shown to have ion channel activity, which may be due to its inhibition of potassium channels. Alpha-Mating Factor is used in research as a tool for studying cell biology and cell signalling pathways.

Formel: C₈₂H₁₁₄N₂₀O₁₇S

Reinheit: Min. 95%

Molekulargewicht: 1,684 g/mol

Ref: 3D-PMF-4076-V

Alpha-Factor

CAS: 59401-28-4

The alpha factor pheromone arrests yeast in the G1 phase of their cell cycle, this allows the opposite mating type cells to synchronise. Alpha factor mating pheromone induces the expression of mating genes, changes in nuclear architecture, and polarizes growth toward the mating partner. STE2 encodes the alpha factor pheromone transmembrane G-protein coupled receptor (GPCR) found on mating-type-A cells in yeast. Alpha factor binds Ste2 and activates prototypic mitogen-activated protein kinase (MAPK) cascade. The dose of pheromone exposure differentially activates the MAPK Fus3 for alternate effects. A high dose of alpha factor leads to growth arrest and schmooing formation for mating, a lower dose causes elongated cell growth.

Formel: C₈₂H₁₁₄N₂₀O₁₇S

Reinheit: Min. 95%

Farbe und Form: Powder

Molekulargewicht: 1,683.97 g/mol

Ref: 3D-CRB1000148

Mating Factor a trifluoroacetate salt

CAS: 59401-28-4

Please enquire for more information about Mating Factor a trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formel: C₈₂H₁₁₄N₂₀O₁₇S·xC₂HF₃O₂

Reinheit: Min. 95%

Molekulargewicht: 1,683.97 g/mol

Ref: 3D-FM108804

Mating factor α trifluoroacetate

CAS: 59401-28-4

Mating factor α trifluoroacetate is a research tool with CAS No. 59401-28-4 that is used in Cell Biology, Pharmacology, and Ion channels. Mating factor α trifluoroacetate inhibits ligand binding to receptor by competing with the natural substrate for the active site. It has been shown to be an activator of ion channels, which allow ions to flow through the cell membrane. Mating factor α trifluoroacetate can also be used as a research tool in antibody production and protein interactions.

Formel: C₈₂H₁₁₄N₂₀O₁₇S

Reinheit: Min. 95%

Molekulargewicht: 1,684.01 g/mol

Ref: 3D-JCA40128