CAS 68-89-3

Metamizol

Beschreibung:

Metamizol, auch bekannt als Metamizol, ist ein nicht-opioides Analgetikum und Antipyretikum, das häufig zur Schmerzlinderung und Fieberreduktion eingesetzt wird. Es wird als Pyrazolon-Derivat klassifiziert und ist bekannt für seine starken schmerzlindernden Eigenschaften. Metamizol wird typischerweise in seiner Natriumsalzform verabreicht, was seine Löslichkeit in Wasser verbessert. Die Verbindung zeichnet sich durch ihre Fähigkeit aus, die Prostaglandinsynthese zu hemmen, wodurch Schmerzen und Entzündungen reduziert werden. Es wird häufig in klinischen Einrichtungen zur Behandlung von starken Schmerzen eingesetzt, insbesondere wenn andere Analgetika unwirksam sind. Allerdings wurde Metamizol mit schweren Nebenwirkungen in Verbindung gebracht, darunter Agranulozytose, ein potenziell lebensbedrohlicher Rückgang der weißen Blutkörperchen, was zu einer eingeschränkten Verwendung in einigen Ländern geführt hat. Die Substanz wird in der Regel gut aufgenommen, wenn sie oral oder intravenös verabreicht wird, und ihre Wirkungen können schnell eintreten, was sie zu einer wertvollen Option in akuten Schmerzsituationen macht. Trotz ihrer Wirksamkeit müssen Gesundheitsdienstleister die Vorteile gegen die Risiken abwägen, wenn sie Metamizol für die Behandlung von Patienten in Betracht ziehen.

Formel: C₁₃H₁₆N₃NaO₄S

InChl: InChI=1/C13H19N3O4S.Na/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11;/h4-8,10,12H,9H2,1-3H3,(H,18,19,20);/q;+1/p-1/rC13H18N3NaO4S/c1-10-12(14(2)9-22(19,20)21-17)13(18)16(15(10)3)11-7-5-4-6-8-11/h4-8,10,12H,9H2,1-3H3

InChI Key: InChIKey=CEOUXRNZHGKECQ-UHFFFAOYSA-N

SMILES: O=C1N(N(C)C(C)=C1N(CS(=O)(=O)O)C)C2=CC=CC=C2.[Na]

Synonyme:

• Algocalmin
• Algopyrin
• Amoloid HV
• Amoloid LV
• Anador
• Analgin
• Analgin DAB10
• Analgine
• Andolor
• Arpf
• Collatex A/RE
• Collatex Arm Extra
• CollatexA/RE Extra
• Conmel
• Diprofarn
• Dipyrone,hydrate
• Duckammon
• E 403
• Gifaril
• Kimica Algin NH
• Kimitsu Algin NH
• Lisador
• Manutex PC-MV
• Metamizol
• Metamizole
• Metamizole Sodium
• Metamizole sodium salt
• Metapyrin
• Methamizole sodium
• Methampyrone
• Methanesulfonic acid, (antipyrinylmethylamino)-, sodium salt
• Methanesulfonic acid, 1-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-, sodium salt (1:1)
• Methanesulfonic acid, [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-, sodium salt
• Methylmelubrin
• Metilon
• Narone
• Natrium-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methansulfonat
• Neo-melubrine
• Noramidopyrine methanesulfonate sodium
• Noramidopyrine methanesulfonate sodium salt
• Noraminophenazone methanesulfonate sodium salt
• Noraminophenazone sodium mesylate
• Novalgetol
• Novalgin
• Novamidazophen
• Novaminophenazone
• Novaminsulfone
• Novaminsulfone sodium
• Novaminsulfonium
• Novaminsulfonum
• Noveltex
• Optalgin
• Pharmalgine
• Protamon S
• Pyralgine
• Pyretin
• Pyretin (pharmaceutical)
• Restriva
• Sodium ((2,3-Dihydro-1,5-Dimethyl-3-Oxo-2-Phenyl-1H-Pyrazol-4-Yl)Methylamino)Methanesulfonate
• Sodium (antipyrinylmethylamino)methanesulfonate
• Sodium 1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonate
• Sodium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonate
• Sodium metamizole
• Sodium noramidopyrine methanesulfonate
• Sodium novaminsulfonate
• Sulpin
• Sulpyrin
• Sulpyrine
• [(1,5-Dimethyl-3-Oxo-2-Phenyl-Pyrazolidin-4-Yl)-Methyl-Amino]Methylsulfonyloxy Sodium
• [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate
• [(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonic acid sodium salt
• [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazole-4-yl)methylamino]methanesulfonate de sodium
• [(2-fenil-2,3-dihidro-1,5-dimetil-3-oxo-1H-pirazol-4-il)metilamino]metanosulfonato de sodio
• sodium [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate
• sodium [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate hydrate (1:1:1)
• Dipyrone
• BENZALAGEN
• (antipyrinylmethylamino)-methanesulfonicacimonosodiumsalt
• SODIUM [(1,5-DIMETHYL-3-OXO-2-PHENYL-PYRAZOL-4-YL)-METHYL-AMINO]METHANESULFONATE
• 4-methylamino-1,5-dimethyl-2-phenyl-3-pyrazolonesodiummethanesulfonate
• (antipyrinylmethylamino)methanesulfonicacidsodiumsalt
• 1-phenyl-2,3-dimethylpyrazolone-(5)-4-methylaminomethanesulfonicacidsodium
• dipyron
• LABOTEST-BB LT00771955
• (antipyrinylmethylamino)-methanesulfonicacisodiumsalt
• DIPYRONE SODIUM
• 1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonatesodium
• METAMIZOL SODIUM
• SODIUM DIPYRONE

Metamizole Sodium Salt

CAS: 68-89-3

Formel: C₁₃H₁₆N₃NaO₄S

Reinheit: >98.0%(T)(HPLC)

Farbe und Form: White to Almost white powder to crystal

Molekulargewicht: 333.34

Ref: 3B-M3060

Dipyrone

CAS: 68-89-3

Formel: C₁₃H₁₇N₃NaO₄S

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 334.3465

Ref: IN-DA006FYJ

Metamizole sodium

CAS: 68-89-3

Metamizole sodium (Analgin) is a drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of AMINOPYRINE.

Formel: C₁₃H₁₆N₃NaO₄S

Reinheit: 99.52%

Farbe und Form: White Or Almost White Crystal Powder

Molekulargewicht: 333.34

Ref: TM-T1191L

Metamizole Sodium Salt (Dipyrone)

CAS: 68-89-3

Formel: C₁₃H₁₆N₃O₄S·Na

Farbe und Form: White To Off-White Solid

Molekulargewicht: 310.35 22.99

Ref: 4Z-M-531

Dipyrone

CAS: 68-89-3

Dipyrone

Reinheit: 98%

Molekulargewicht: 333.34g/mol

Ref: 54-OR1029314

Metamizole sodium

CAS: 68-89-3

Metamizole sodium

Reinheit: ≥98%

Molekulargewicht: 333.34g/mol

Ref: 54-BUP10835

Metamizol sodium

Kontrolliertes Produkt

CAS: 68-89-3

Formel: C₁₃H₁₆N₃O₄S·Na

Farbe und Form: White

Molekulargewicht: 333.34

Ref: 04-C14942000

Dipyrone

Kontrolliertes Produkt

CAS: 68-89-3

Applications Dipyrone is a non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Dipyrone blocks PGE2-induced hyperalgesia in several models. Neuroprotective & Neuroresearch Product.
References Reith, J., et al.: Lancet, 347, 422 (1996), Grau, A., et al.: J. Neurol. Sci., 171, 115 (1999), Schwarz, S., et al.: Neurology, 2000, 54, 354 (2000), Greer, D., et al.: Stroke, 39, 3029 (2008),

Formel: C₁₃H₁₆N₃O₄S·Na

Farbe und Form: Neat

Molekulargewicht: 333.34

Ref: TR-D492860

Dipyrone-d3

Kontrolliertes Produkt

CAS: 68-89-3

Stability Hygroscopic
Applications Labelled Dipyrone. Dipyrone is a non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Dipyrone blocks PGE2-induced hyperalgesia in several models.
References Reith, J. et al.: Lancet, 347, 422 (1996); Grau, A. et al.: J. Neurol. Sci., 171, 115 (1999); Schwarz, S. et al.: Neurology, 2000, 54, 354 (2000); Greer, D. et al.: Stroke, 39, 3029 (2008);

Formel: C₁₃H₁₃D₃N₃NaO₄S

Farbe und Form: Off-White

Molekulargewicht: 336.36

Ref: TR-D492862

Dipyrone

CAS: 68-89-3

Dipyrone is an anti-inflammatory and analgesic drug that belongs to the group of non-steroidal anti-inflammatory drugs. It has been shown to inhibit the production of prostaglandins, which are involved in inflammation, by inhibiting cyclooxygenase. The polymerase chain reaction (PCR) method is a biochemical technique used to amplify a segment of DNA, typically for use as a genetic marker or for cloning a particular gene. A PCR assay can be used to detect the presence of bacterial DNA in a sample. Dipyrone has been shown to possess chemiluminescence activity, which is indicative of its ability to bind with DNA. This binding inhibits transcription and replication and may be responsible for the toxic effects on epidermal cells observed in animal studies. Dipyrone also has been shown to have anti-inflammatory activities through its inhibition of cyclooxygenase and its ability to inhibit neutrophil migration and function.

Formel: C₁₃H₁₆N₃NaO₄S

Reinheit: Min. 95%

Farbe und Form: White Solid

Molekulargewicht: 333.34 g/mol

Ref: 3D-FD22539

Dipyrone Sodium Salt

CAS: 68-89-3

Formel: C₁₃H₁₆N₃O₄SNa

Molekulargewicht: 310.3 : 23.0

Ref: ST-EA-CP-A231001