CAS 68767-14-6

Loxoprofen

Beschreibung:

Loxoprofen ist ein nichtsteroidales entzündungshemmendes Medikament (NSAID), das hauptsächlich wegen seiner schmerzlindernden und entzündungshemmenden Eigenschaften eingesetzt wird. Es wird häufig zur Behandlung von Schmerzen und Entzündungen eingesetzt, die mit Erkrankungen wie Arthritis, Muskelschmerzen und postoperativen Beschwerden verbunden sind. Loxoprofen wirkt, indem es die Cyclooxygenase (COX)-Enzyme hemmt, die eine entscheidende Rolle bei der Synthese von Prostaglandinen spielen, Verbindungen, die Entzündungen und Schmerzen vermitteln. Die Substanz zeichnet sich durch einen relativ schnellen Wirkungseintritt aus und wird häufig in verschiedenen Darreichungsformen formuliert, einschließlich Tabletten und topischen Anwendungen. Loxoprofen ist bekannt für sein günstiges gastrointestinales Sicherheitsprofil im Vergleich zu anderen NSAIDs, was es in bestimmten klinischen Szenarien zur bevorzugten Wahl macht. Wie alle Medikamente kann es jedoch Nebenwirkungen haben, einschließlich gastrointestinaler Störungen, kardiovaskulärer Risiken und potenzieller Wechselwirkungen mit anderen Arzneimitteln. Seine chemische Struktur umfasst ein Derivat der Propionsäure, das zu seiner pharmakologischen Aktivität beiträgt. Wie bei jedem Medikament ist es wichtig, Loxoprofen unter ärztlicher Aufsicht zu verwenden, um Sicherheit und Wirksamkeit zu gewährleisten.

Formel: C₁₅H₁₈O₃

InChl: InChI=1S/C15H18O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13H,2-4,9H2,1H3,(H,17,18)

InChI Key: InChIKey=YMBXTVYHTMGZDW-UHFFFAOYSA-N

SMILES: C(C1=CC=C(C(C(O)=O)C)C=C1)C2C(=O)CCC2

Synonyme:

• 2-[4-(2-Oxo-Cyclopentylmethyl)-Phenyl]-Propionic Acid
• 2-[4-[(2-Oxocyclopentan-1-Yl)Methyl]Phenyl]Propionic Acid
• 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionic acid
• 2-{4-[(2-Oxocyclopentyl)Methyl]Phenyl}Propanoic Acid
• A-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid
• Alpha-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid
• Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-
• Ioxoprofen
• Koloxo
• Loxoprofen Acid
• ��-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid

Loxoprofen

CAS: 68767-14-6

Formel: C₁₅H₁₈O₃

Reinheit: >97.0%(T)(HPLC)

Farbe und Form: White to Light yellow powder to crystal

Molekulargewicht: 246.31

Ref: 3B-L0244

Loxoprofen

CAS: 68767-14-6

Loxoprofen (Koloxo) is an anti-inflammatory non-steroidal medicine.

Formel: C₁₅H₁₈O₃

Reinheit: 98.59%

Farbe und Form: White To Yellowish Crystalline Powder

Molekulargewicht: 246.3

Ref: TM-T0463

Loxoprofen

CAS: 68767-14-6

Formel: C₁₅H₁₈O₃

Reinheit: 97%

Farbe und Form: Solid

Molekulargewicht: 246.3016

Ref: IN-DA003RD6

Loxoprofen Impurity 1 and Loxoprofen Impurity 50

CAS: 68767-14-6

Formel: C₁₈H₂₄O₅

Molekulargewicht: 320.39

Ref: 4Z-L-8978

Loxoprofen

CAS: 68767-14-6

Formel: C₁₅H₁₈O₃

Reinheit: ≥ 97.0%

Farbe und Form: White to faint yellow crystalline powder

Molekulargewicht: 246.30

Ref: 7W-GP1810

Loxoprofen-d4

CAS: 68767-14-6

Formel: C₁₅H₁₄D₄O₃

Farbe und Form: White To Off-White Solid

Molekulargewicht: 250.33

Ref: 4Z-L-8921

Loxoprofen

CAS: 68767-14-6

Loxoprofen

Reinheit: ≥98%

Molekulargewicht: 246.3g/mol

Ref: 54-BUP15038

Loxoprofen

CAS: 68767-14-6

Loxoprofen

Reinheit: 98%

Molekulargewicht: 246.3g/mol

Ref: 54-OR1030277

Loxoprofen

CAS: 68767-14-6

Formel: C₁₅H₁₈O₃

Farbe und Form: Off-White Solid

Molekulargewicht: 246.31

Ref: 4Z-L-891

Loxoprofen Sodium Salt Dihydrate

CAS: 226721-96-6, 68767-14-6, 80382-23-6

Formel: C₁₅H₁₇NaO₃·2H₂O

Reinheit: >98.0%(T)(HPLC)

Farbe und Form: White to Almost white powder to crystal

Molekulargewicht: 304.32

Ref: 3B-L0252

Loxoprofen-d6

CAS: 68767-14-6

Formel: C₁₅H₁₂D₆O₃

Molekulargewicht: 252.35

Ref: 4Z-L-897

Loxoprofen RS

CAS: 68767-14-6

Farbe und Form: White Solid Crystalline Powder

Ref: 2K-1188000021

Loxoprofen

Kontrolliertes Produkt

CAS: 68767-14-6

Applications Loxoprofen is a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Loxoprofen becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.
References Masahide H. et al.: J Clin Biochem Nutr., 47, 138 (2010); Noguchi, M. et al.: Biolog. Pharmac. Bull., 28, 2075 (2005); Hyun, J. et al.: Arch. Pharm. Res., 24, 541 (2001);

Formel: C₁₅H₁₈O₃

Farbe und Form: White To Off-White

Molekulargewicht: 246.3

Ref: TR-L472905

Loxoprofen-d3

Kontrolliertes Produkt

CAS: 68767-14-6

Applications Loxoprofen-d3, is the labeled analogue of Loxoprofen (L472905), which is non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation.
References Masahide H. et al.: J Clin Biochem Nutr., 47, 138 (2010); Noguchi, M. et al.: Biolog. Pharmac. Bull., 28, 2075 (2005); Hyun, J. et al.: Arch. Pharm. Res., 24, 541 (2001);

Formel: C₁₅H₁₅D₃O₃

Farbe und Form: Neat

Molekulargewicht: 249.32

Ref: TR-L472907

Loxoprofen (high-melting polymorph)

CAS: 68767-14-6

Loxoprofen is a nonsteroidal anti-inflammatory drug that belongs to the group of drugs called NSAIDs. It has potent inhibitory activity against growth factor, which is important for the promotion of inflammation and tissue damage in diseases such as rheumatoid arthritis. Loxoprofen has been shown to have strong inhibitory effects on bacterial translocation in mice with colitis, which may be related to its ability to decrease the expression of endogenous substances through inhibition of colony-stimulating factor. Loxoprofen also has a high solubility in water (2g/L) and is soluble in biocompatible polymers such as polyvinylpyrrolidone.

Formel: C₁₅H₁₈O₃

Reinheit: Min. 95%

Farbe und Form: Powder

Molekulargewicht: 246.31 g/mol

Ref: 3D-FL172231

Loxoprofen (high-melting polymorph)

CAS: 68767-14-6

Loxoprofen is a high-melting polymorph of loxoprofen, which is a nonsteroidal anti-inflammatory drug. Loxoprofen is used for the relief of pain and inflammation in patients with rheumatoid arthritis and osteoarthritis. It has been shown to be useful as an intermediate in the synthesis of other compounds, such as pharmaceuticals, pesticides, and dyes. Loxoprofen has also been found to be a useful building block in organic synthesis reactions that require high quality reagents.

Formel: C₁₅H₁₈O₃

Reinheit: Min. 98.5 Area-%

Molekulargewicht: 246.31 g/mol

Ref: 3D-Q-201324

2-(4-((2-Oxocyclopentyl)methyl)phenyl)propanoic acid

CAS: 68767-14-6

Formel: C₁₅H₁₈O₃

Reinheit: 95%

Farbe und Form: Solid

Molekulargewicht: 246.306

Ref: 10-F093438

Loxoprofen (low-melting polymorph)

CAS: 68767-14-6

Loxoprofen is a non-steroidal anti-inflammatory drug that belongs to the class of drugs called pyrazoles. It is used in the treatment of inflammation and pain caused by arthritis, osteoarthritis, gout, menstrual pain, and dental pain. Loxoprofen binds to cyclooxygenase (COX) enzymes, thereby inhibiting prostaglandin synthesis. The COX enzymes are necessary for the production of prostaglandins that lead to inflammation and pain. Loxoprofen also inhibits bacterial translocation by binding to bacterial lipopolysaccharides on the cell surface and preventing their interaction with immune cells. Loxoprofen has been shown to inhibit colony stimulating factor (CSF) activity in vitro assays by disrupting CSF-1 binding to its receptor erythropoietin receptor or CD11b/CD18 integrin receptors on monocytes or neutrophils. This means that it will not stimulate the

Formel: C₁₅H₁₈O₃

Reinheit: Min. 95%

Farbe und Form: Powder

Molekulargewicht: 246.3 g/mol

Ref: 3D-FL172228

Loxoprofen (low-melting polymorph)

CAS: 68767-14-6

Loxoprofen is a chemical intermediate that can be used to synthesize complex molecules. It has been shown to have many uses in the laboratory as a reaction component, reagent, or as a useful scaffold for research chemicals. Loxoprofen is also an effective building block for more complex compounds and can be used to synthesize speciality chemicals such as fine chemicals and pharmaceuticals. Loxoprofen is a white solid with low melting point that can be dissolved in organic solvents such as dichloromethane and chloroform.

Formel: C₁₅H₁₈O₃

Reinheit: Min. 98.5 Area-%

Molekulargewicht: 246.31 g/mol

Ref: 3D-Q-300011