CAS 7103-27-7

N3-Methyl-2'-O-methyluridine

CAS: 7103-27-7

Nucleoside Derivatives - N-Methylated nucleosides, Naturally modified Ribo-nucleosides

Formel: C₁₁H₁₆N₂O₆

Farbe und Form: Solid

Molekulargewicht: 272.25

Ref: TM-TNU0374

3,2’-O-Dimethyluridine

Kontrolliertes Produkt

CAS: 7103-27-7

Formel: C₁₁H₁₆N₂O₆

Farbe und Form: White To Off-White

Molekulargewicht: 272.254

Ref: TR-D465945

N3-Methyl-2'-O-methyluridine

CAS: 7103-27-7

2'-O-methyluridine is an antiviral nucleoside that is used as a phosphoramidite in the synthesis of oligonucleotides. It has been shown to inhibit viral replication, and has been found to be effective in treating HIV-1 by inhibiting reverse transcriptase. N3-Methyl-2'-O-methyluridine also inhibits DNA synthesis and cell proliferation, and may be useful for the treatment of cancer. This modified nucleoside has been synthesized from uracil and contains a methyl group at the 3' position. The methyl group prevents 2'-O-methyluridine from being activated by cellular thymidylate synthase, which normally converts deoxyribonucleotides into ribonucleotides. This novel nucleotide has not yet been used in clinical trials but it may provide an alternative to other drugs used for cancer treatments.

Formel: C₁₁H₁₆N₂O₆

Reinheit: Min. 95 Area-%

Farbe und Form: White Off-White Powder

Molekulargewicht: 272.25 g/mol

Ref: 3D-NM163076