CAS 71989-23-6

N-Fmoc-L-Isoleucin

Beschreibung:

N-Fmoc-L-Isoleucin ist ein Derivat der Aminosäure Isoleucin, das durch das Vorhandensein einer 9-Fluorenylmethoxycarbonyl (Fmoc) Schutzgruppe am Aminoterminus gekennzeichnet ist. Diese Verbindung wird häufig in der Peptidsynthese als Baustein verwendet, da sie stabil ist und die Entfernung der Fmoc-Gruppe unter milden basischen Bedingungen einfach ist. N-Fmoc-L-Isoleucin behält die wesentlichen Eigenschaften der Isoleucin bei, einschließlich ihrer hydrophoben Natur und der Fähigkeit, an verschiedenen Wechselwirkungen innerhalb von Peptidketten teilzunehmen. Die Fmoc-Gruppe verbessert die Löslichkeit der Aminosäure in organischen Lösungsmitteln und erleichtert ihre Einbindung in Peptide. Darüber hinaus ist N-Fmoc-L-Isoleucin typischerweise weiß bis cremefarben und in gängigen organischen Lösungsmitteln wie Dimethylformamid (DMF) und Dimethylsulfoxid (DMSO) löslich. Seine molekulare Struktur ermöglicht die Bildung stabiler Peptidbindungen, was es zu einem wertvollen Bestandteil bei der Synthese biologisch aktiver Peptide und Proteine macht.

Formel: C₂₁H₂₃NO₄

InChl: InChI=1S/C21H23NO4/c1-3-13(2)19(20(23)24)22-21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,3,12H2,1-2H3,(H,22,25)(H,23,24)/t13-,19-/m0/s1

InChI Key: InChIKey=QXVFEIPAZSXRGM-DJJJIMSYSA-N

SMILES: C(OC(N[C@@H]([C@H](CC)C)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Synonyme:

• (2S,3R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-methylpentanoate
• (2S,3S)-2-(((9-Fluorenylmethoxy)carbonyl)amino)-3-methylpentanoic acid
• 2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-methylpentanoic acid
• <span class="text-smallcaps">L</span>-Isoleucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-Ile-OH
• Fmoc-L-isoleucine
• Fmoc-lle-OH
• N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-isoleucine
• N-(9-Fluorenylmethoxycarbonyl)isoleucine
• N-Fmoc-<span class="text-smallcaps">L</span>-isoleucine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-isoleucine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]isoleucin
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]isoleucine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alloisoleucine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-isoleucine
• NSC 334289
• isoleucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• N-(9-Fluorenylmethoxycarbonyl)-L-isoleucine
• L-Isoleucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine

CAS: 71989-23-6

Formel: C₂₁H₂₃NO₄

Farbe und Form: White to Almost white powder to crystal

Molekulargewicht: 353.42

Ref: 3B-F0294

Fmoc-Ile-OH

CAS: 71989-23-6

Bachem ID: 4003168.

Formel: C₂₁H₂₃NO₄

Reinheit: 99.87%

Farbe und Form: White

Molekulargewicht: 353.42

Ref: 01-4003168

Fmoc-L-Isoleucine

CAS: 71989-23-6

Formel: C₂₁H₂₃NO₄

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 353.4116

Ref: IN-DA0036PS

Fmoc-Ile-OH

CAS: 71989-23-6

Fmoc-Ile-OH

Reinheit: ≥98%

Molekulargewicht: 353.41g/mol

Ref: 54-BUP19430

Fmoc-Ile-OH

CAS: 71989-23-6

Formel: C₂₁H₂₃NO₄

Reinheit: ≥ 99.0%

Farbe und Form: White powder

Molekulargewicht: 353.42

Ref: 7W-GM4384

Fmoc-lle-OH

CAS: 71989-23-6

M03362 - Fmoc-lle-OH

Formel: C₂₁H₂₃NO₄

Reinheit: 98%

Farbe und Form: Powder or Crystalline Powder

Molekulargewicht: 353.418

Ref: 10-M03362

Fmoc-Ile-OH

CAS: 71989-23-6

Fmoc-Ile-OH (Fmoc-L-isoleucine) is an Fmoc-modified isoleucine with a strong affinity for peptides and proteins and can be used to synthesize other active

Formel: C₂₁H₂₃NO₄

Reinheit: 99.75%

Farbe und Form: Solid

Molekulargewicht: 353.41

Ref: TM-T67562

L-Isoleucine, FMOC protected

CAS: 71989-23-6

L-Isoleucine, FMOC protected

Formel: C₂₁H₂₃NO₄

Reinheit: 95%

Farbe und Form: white powder

Molekulargewicht: 353.41g/mol

Ref: 54-OR0490

Fmoc-Ile-OH (N-Fmoc-L-isoleucine)

CAS: 71989-23-6

Formel: C₂₁H₂₃NO₄

Molekulargewicht: 353.42

Ref: 4Z-L-117014

Fmoc-Ile-OH

CAS: 71989-23-6

Fmoc-Ile-OH is a sodium salt that is used in the synthesis of peptides. It provides the hydroxyl group to the peptide chain, and can be used in solid-phase synthesis. The protonated form of Fmoc-Ile-OH is useful for acetonitrile solvents. Fmoc-Ile-OH has shown antibacterial activity against gram-positive bacteria such as Staphylococcus aureus and Streptococcus pneumoniae. Clinical development of this drug has been successful in treating infections caused by multidrug resistant bacteria, such as MRSA, Acinetobacter baumannii, and Pseudomonas aeruginosa.

Formel: C₂₁H₂₃NO₄

Reinheit: Min. 98.0 Area-%

Molekulargewicht: 353.42 g/mol

Ref: 3D-FLI-1724-PI

FMOC-L-Isoleucine extrapure, 99%

CAS: 71989-23-6

Formel: C₂₁H₂₃NO₄

Reinheit: min. 99%

Farbe und Form: White, Crystalline powder

Molekulargewicht: 353.40

Ref: SR-22834

N-Fmoc-L-isoleucine

Kontrolliertes Produkt

CAS: 71989-23-6

Applications N-Fmoc-L-isoleucine is a N-Fmoc-protected form of L-Isoleucine (I820175). L-Isoleucine is classified as an essential amino acid, and is also a tumour promoter of bladder cancer in rats.
References Hatch, T., et al.: Infect. Immun., 12, 211 (1975); Nishio, Y., et al.: Science, 231, 843 (1986)

Formel: C₂₁H₂₃NO₄

Farbe und Form: Neat

Molekulargewicht: 353.41

Ref: TR-F625025

N-Fmoc-L-isoleucine-d10

Kontrolliertes Produkt

CAS: 71989-23-6

Applications N-Fmoc-L-isoleucine-d10 is the labeled analogue of N-Fmoc-L-isoleucine (F625025), a N-Fmoc-protected form of L-Isoleucine (I820175). L-Isoleucine is classified as an essential amino acid, and is also a tumour promoter of bladder cancer in rats.
References Hatch, T., et al.: Infect. Immun., 12, 211 (1975); Nishio, Y., et al.: Science, 231, 843 (1986)

Formel: C₂₁D₁₀H₁₃NO₄

Farbe und Form: Neat

Molekulargewicht: 363.473

Ref: TR-F625027

Fmoc-Ile-OH

CAS: 71989-23-6

Fmoc-Ile-OH is a cyclic peptide that has shown cytotoxic activity against cultured human brain cells. It is also an inhibitor of dipeptidyl peptidase IV (DPP-IV) and inhibits the breakdown of proteins in the brain, such as insulin. Fmoc-Ile-OH binds to the active site of DPP-IV and prevents it from binding to its substrate, thereby inhibiting the enzyme's activity. The inhibition of DPP-IV leads to increased levels of protein in the brain, which may be beneficial for people with Alzheimer's disease. Fmoc-Ile-OH is synthesized on a solid phase by coupling an amino acid with a protected carboxylic acid to yield a protected amide. This product can be used as an encapsulating agent for atosiban, a drug that is used to treat preterm labor.END>>

Formel: C₂₁H₂₃NO₄

Reinheit: Min. 98 Area-%

Farbe und Form: White Off-White Powder

Molekulargewicht: 353.41 g/mol

Ref: 3D-FF15881