CAS 72957-38-1

Dynorphin A Fragment 1-13

Beschreibung:

Dynorphin A Fragment 1-13 ist ein Peptid, das aus dem größeren Molekül Dynorphin A abgeleitet ist, das Teil der Familie der endogenen Opioidpeptide ist. Dieses Fragment besteht aus 13 Aminosäuren und ist bekannt für seine Rolle bei der Modulation von Schmerz, Stressreaktionen und verschiedenen neurophysiologischen Prozessen. Es interagiert hauptsächlich mit den Kappa-Opioid-Rezeptoren im zentralen Nervensystem und trägt zu seinen schmerzlindernden Effekten bei. Das Peptid weist typische Eigenschaften von Opioidpeptiden auf, einschließlich der Fähigkeit, Analgesie zu induzieren und Stimmung sowie emotionale Reaktionen zu beeinflussen. Seine Struktur umfasst spezifische Sequenzen, die entscheidend für die Rezeptorbindung und -aktivität sind. Darüber hinaus kann Dynorphin A Fragment 1-13 Implikationen für verschiedene neurologische Erkrankungen haben und ist von Interesse in der Forschung zu Sucht, Depression und anderen Stimmungsstörungen. Als synthetisches oder natürlich vorkommendes Peptid kann es hinsichtlich seiner pharmakologischen Eigenschaften und potenziellen therapeutischen Anwendungen untersucht werden.

Formel: C₇₅H₁₂₆N₂₄O₁₅

InChl: InChI=1/C75H126N24O15/c1-7-45(6)61(70(111)94-53(25-17-35-87-75(83)84)71(112)99-36-18-26-58(99)69(110)93-50(21-11-13-31-76)64(105)96-56(38-44(4)5)67(108)95-54(72(113)114)22-12-14-32-77)98-65(106)52(24-16-34-86-74(81)82)91-63(104)51(23-15-33-85-73(79)80)92-66(107)55(37-43(2)3)97-68(109)57(40-46-19-9-8-10-20-46)90-60(102)42-88-59(101)41-89-62(103)49(78)39-47-27-29-48(100)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,100H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H,88,101)(H,89,103)(H,90,102)(H,91,104)(H,92,107)(H,93,110)(H,94,111)(H,95,108)(H,96,105)(H,97,109)(H,98,106)(H,113,114)(H4,79,80,85)(H4,81,82,86)(H4,83,84,87)/t45-,49-,50-,51-,52-,53-,54?,55-,56-,57-,58-,61-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=N[C@@H](CCCCN)C(=N[C@@H](CC(C)C)C(=NC(CCCCN)C(=O)O)O)O)O)O)N=C([C@H](CCCNC(=N)N)N=C([C@H](CCCNC(=N)N)N=C([C@H](CC(C)C)N=C([C@H](Cc1ccccc1)N=C(CN=C(CN=C([C@H](Cc1ccc(cc1)O)N)O)O)O)O)O)O)O

Synonyme:

• Dynorphin A (1-13)
• H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH
• Dynorphin A 1-13, Porcine

Dynorphin A (1-13)

CAS: 72957-38-1

Endogenous kappa-opioid receptor agonist. It is suggested that it attenuates galanin-induced impairment of memory processes through the mediation of kappa-opioid receptors.

Formel: C₇₅H₁₂₆N₂₄O₁₅

Reinheit: 91.6%

Farbe und Form: White Powder

Molekulargewicht: 1603.98

Ref: 01-4004062

Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH

CAS: 72957-38-1

Formel: C₇₅H₁₂₆N₂₄O₁₅

Reinheit: 98%

Molekulargewicht: 1603.9547

Ref: IN-DA01E9V2

Dynorphin A (1-13) Acetatexa0

CAS: 72957-38-1

Ref: 7W-GX0937

Dynorphin A(1-13) Acetate

CAS: 72957-38-1

Formel: C₇₅H₁₂₆N₂₄O₁₅

Reinheit: 95%~99%

Farbe und Form: White to Off-white Powder

Molekulargewicht: 1603.97

Ref: BP-BPPG022

Porcine dynorphin A(1-13)

CAS: 72957-38-1

Porcine dynorphin A (1-13) is a potent κ opioid receptor agonist; it's antinociceptive and raises [Ca2+]i in neurons like NMDA.

Formel: C₇₅H₁₂₆N₂₄O₁₅

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 1603.95

Ref: TM-TP1179

Porcine Dynorphin A(1-13)

CAS: 72957-38-1

Porcine Dynorphin A(1-13)

Reinheit: 99%

Molekulargewicht: 1,603.95g/mol

Ref: 54-BISN0009

Dynorphin A (1-13)

CAS: 72957-38-1

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formel: C₇₅H₁₂₆N₂₄O₁₅

Molekulargewicht: 1,603.95 g/mol

Ref: 3D-PP50465

Dynorphin A (1-12), porcine

CAS: 72957-38-1

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formel: C₆₉H₁₁₄N₂₂O₁₄

Molekulargewicht: 1,475.82 g/mol

Ref: 3D-PP50361

Dynorphin A (porcine 1-13) - acetate salt

CAS: 72957-38-1

Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys is a peptide that is found in the brain and spinal cord. It is an agonist of opioid receptors, which are involved in pain relief, as well as motor control. Dynorphin A (1-13) H has been shown to inhibit acetylcholine release, which may be due to its ability to bind to kappa opioid receptors. Dynorphin A (1-13) H is also known to bind to κ opioid receptors, where it inhibits locomotor activity and induces analgesia.

Formel: C₇₅H₁₂₆N₂₄O₁₅

Reinheit: Min. 95%

Farbe und Form: Powder

Molekulargewicht: 1,603.96 g/mol

Ref: 3D-FD108725

Dynorphin A (1-13), Porcine

CAS: 72957-38-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Farbe und Form: Lyophilized powder

Ref: 02-J64015

Dynorphin A (Human, 1-13)

CAS: 72957-38-1

As a dynorphin peptide, Dynorphin A has affinity for opioid receptors in particular it favors kappa-opioid receptors and residues 1-13 of the Dynorphin A peptide are crucial for its potency. Kappa-opioid receptors are expressed in the brain, peripheral tissues and the spinal cord and are located in areas involved in pain. For example when Dynorphin A binds to kappa-opioid receptors, dopamine is inhibited in areas of the brain prevalent in drug addiction, thus demonstrated Dynorphin A to have antagonistic effects on the brain reward circuit. Dynorphin A could be a useful research tool for studying analgesia, reward and addiction.
This product is available as a 0.5mg vial.

Formel: C₇₅H₁₂₆N₂₄O₁₅

Reinheit: Min. 95%

Molekulargewicht: 1,604 g/mol

Ref: 3D-PDY-4080-V