CAS 7772-94-3

2-(Acetylamino)-2-desoxy-β-D-mannopyranose

Beschreibung:

2-(Acetylamino)-2-desoxy-β-D-mannopyranose, allgemein bekannt als N-Acetylmannosamin, ist ein Aminozucker, der eine bedeutende Rolle in verschiedenen biologischen Prozessen spielt, insbesondere bei der Synthese von Glykoproteinen und Glykolipiden. Diese Verbindung weist eine Acetylamino-Gruppe an der C-2-Position des Mannopyranoserings auf, was zu ihren biochemischen Eigenschaften beiträgt. Sie ist typischerweise ein weißer bis cremefarbener kristalliner Feststoff, der in Wasser löslich ist, was ihre polare Natur aufgrund der Hydroxyl- und Aminogruppen widerspiegelt. Das Vorhandensein der Acetylamino-Gruppe erhöht ihre Reaktivität und ermöglicht es ihr, an verschiedenen Stoffwechselwegen teilzunehmen, einschließlich derjenigen, die an der Biosynthese von Sialinsäure beteiligt sind. N-Acetylmannosamin ist auch wichtig für Zell-Signalübertragungs- und Erkennungsprozesse, was sie zu einem interessanten Thema in der Forschung über zelluläre Interaktionen und Krankheitsmechanismen macht. Ihre CAS-Nummer, 7772-94-3, wird zur Identifizierung in chemischen Datenbanken und regulatorischen Kontexten verwendet. Insgesamt ist diese Verbindung sowohl in der Biochemie als auch in pharmazeutischen Anwendungen von Bedeutung.

Formel: C₈H₁₅NO₆

InChl: InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5+,6-,7-,8-/m1/s1

InChI Key: InChIKey=OVRNDRQMDRJTHS-OZRXBMAMSA-N

SMILES: N(C(C)=O)[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O

Synonyme:

• 2-(Acetylamino)-2-Deoxyhexopyranose Hydrate
• 2-(Acetylamino)-2-deoxy-β-<span class="text-smallcaps">D</span>-mannopyranose
• 2-(acetylamino)-2-deoxy-alpha-D-gulopyranose
• Mannopyranose, 2-acetamido-2-deoxy-, β-<span class="text-smallcaps">D</span>-
• N-Acetyl-D-mannosamine monohydrate
• β-<span class="text-smallcaps">D</span>-Mannopyranose, 2-(acetylamino)-2-deoxy-
• 2-(Acetylamino)-2-deoxy-β-D-mannopyranose
• β-D-Mannopyranose, 2-(acetylamino)-2-deoxy-
• Mannopyranose, 2-acetamido-2-deoxy-, β-D-

N-Acetylmannosamine

CAS: 7772-94-3

Formel: C₈H₁₅NO₆

Reinheit: 95%

Farbe und Form: Solid

Molekulargewicht: 221.2078

Ref: IN-DA003SOW

N-Acetyl-D-mannosamine

CAS: 7772-94-3

Formel: C₈H₁₅NO₆·xH₂O

Reinheit: ≥ 98.0%

Farbe und Form: White to off-white powder

Molekulargewicht: 221.21 (anhydrous)

Ref: 7W-GK3319

2-(Acetamido)-2-deoxy-β-D-mannopyranose

CAS: 7772-94-3

2-(Acetamido)-2-deoxy-β-D-mannopyranose

Reinheit: 97% (Monohydrate)

Molekulargewicht: 221.21g/mol

Ref: 54-OR8153

N-Acetyl-D-mannosamine

CAS: 7772-94-3

N-Acetyl-D-mannosamine

Farbe und Form: White To Off White Powder

Molekulargewicht: 239.22g/mol

Ref: 54-BIA1221

Cyclic N-Acetyl-D-mannosamine

CAS: 7772-94-3

Cyclic N-Acetyl-D-mannosamine is used for sialic acid synthesis and as a precursor for biologically active compounds.

Formel: C₈H₁₅NO₆

Reinheit: 99.18% - 99.72%

Farbe und Form: White Crystal Powder

Molekulargewicht: 221.21

Ref: TM-T4725

N-Acetyl-D-mannosamine

CAS: 7772-94-3

N-Acetyl D-mannosamine (ManNAc) is an aldohexose (2-acetamido-2-deoxymannose) in which the axial hydroxyl group at position 2 is replaced by a N-acetyl group (Collins, 2006). It has been reported that N-acetyl D-mannosamine supplementation, may provide novel means to break the link between obesity and hypertension (Peng, 2019). N-Acetyl-D-mannosamine and N-acetyl-D-glucosamine are the essential precursors of sialic acid, the specific monomer of polysialic acid, a bacterial pathogenic determinant, for example, Escherichia coli K1 uses both amino sugars as carbon sources. Glycoproteins normally have some level of glycan sialylation, but incomplete sialylation can reduce their therapeutic effect when produced recombinantly. To improve performance, cell lines and culture media can be adjusted. The GNE enzyme controls the efficiency of sialylation in human cell lines, making it crucial for producing effective recombinant glycoprotein drugs. Adding ManNAc and other supplements to culture media improves sialylation, which boosts drug yield, increases stability and half-life, and lowers immune reactions by reducing antibody formation.It has also been reported that ManNAc can be used as a treatment for hereditary inclusion body myopathy, an adult-onset, progressive neuromuscular disorder and also for renal disorders involving proteinuria and hematuria due to podocytopathy and/or segmental splitting of the glomerular basement membrane (Galeano, 2007).

Formel: C₈H₁₅NO₆

Reinheit: Min. 97.5 Area-%

Molekulargewicht: 221.21 g/mol

Ref: 3D-Z-1000

N-Acetyl-D-mannosamine - low endotoxin grade

CAS: 7772-94-3

Please enquire for more information about N-Acetyl-D-mannosamine - low endotoxin grade including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formel: C₈H₁₅NO₆

Molekulargewicht: 221.21 g/mol

Ref: 3D-Z-1082

N-Acetyl-D-mannosamine

CAS: 7772-94-3

Reinheit: 95%

Molekulargewicht: 221.21

Ref: 10-F493709

N-Acetyl-D-mannosamine

CAS: 7772-94-3

N-Acetyl D-mannosamine (ManNAc) is an aldohexose (2-acetamido-2-deoxymannose) in which the axial hydroxyl group at position 2 is replaced by a N-acetyl group (Collins, 2006). It has been reported that N-acetyl D-mannosamine supplementation, may provide novel means to break the link between obesity and hypertension (Peng, 2019). N-Acetyl-D-mannosamine and N-acetyl-D-glucosamine are the essential precursors of sialic acid, the specific monomer of polysialic acid, a bacterial pathogenic determinant, for example, Escherichia coli K1 uses both amino sugars as carbon sources. It has been reported that ManNAc can be used as a treatment for hereditary inclusion body myopathy, an adult-onset, progressive neuromuscular disorder and also for renal disorders involving proteinuria and hematuria due to podocytopathy and/or segmental splitting of the glomerular basement membrane (Galeano, 2007).

Formel: C₈H₁₅NO₆

Reinheit: Min. 98 Area-%

Farbe und Form: White Powder

Molekulargewicht: 221.21 g/mol

Ref: 3D-MA05269