![1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F386020-okadaic-acid.webp&w=3840&q=75)
CAS 78111-17-8
:1,7-Dioxaspiro[5.5]undec-10-en-2-propansäure, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, (αR,2S,5R,6R,8S)-
Beschreibung:
1,7-Dioxaspiro[5.5]undec-10-en-2-propansäure, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, (αR,2S,5R,6R,8S)- ist eine komplexe organische Verbindung, die durch ihre komplizierte molekulare Struktur gekennzeichnet ist, die mehrere funktionelle Gruppen wie Dioxaspiro, Hydroxyl und Propansäure-Moieties umfasst. Diese Verbindung zeigt Chiralität, angezeigt durch ihre stereochemischen Deskriptoren, was darauf hindeutet, dass sie in mehreren enantiomeren Formen existieren kann. Ihre strukturelle Komplexität kann einzigartige chemische Eigenschaften verleihen, die potenziell ihre Reaktivität und Interaktionen mit biologischen Systemen beeinflussen. Das Vorhandensein mehrerer Ringe und Stereozentren deutet darauf hin, dass sie Anwendungen in der Pharmazie oder als synthetischer Zwischenstoff in der organischen Chemie haben könnte. Darüber hinaus ermöglicht die CAS-Nummer der Verbindung, 78111-17-8, eine einfache Identifizierung und Referenzierung in chemischen Datenbanken. Insgesamt stellt diese Substanz ein faszinierendes Beispiel für die moderne organische Synthese und strukturelle Vielfalt in chemischen Verbindungen dar.
Formel:C44H68O13
InChl:InChI=1/C44H68O13/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49)/b10-9+/t26-,27-,28+,30+,31+,32+,33-,34+,35-,36-,37?,38+,39?,41-,42+,43-,44-/m1/s1
InChI Key:InChIKey=QNDVLZJODHBUFM-WFXQOWMNSA-N
SMILES:O[C@H]1[C@@]2(O[C@]([C@@H](/C=C/[C@@H]3O[C@]4(CC3)O[C@@]5([C@@](CC4)(O[C@]([C@H](C[C@H](C)[C@]6(O[C@]7(CC[C@H]6C)CCCCO7)[H])O)(C(=C)[C@H]5O)[H])[H])[H])C)(CC(C)=C2)[H])O[C@H](C[C@@](C(O)=O)(C)O)CC1
Synonyme:- (αR,2S,5R,6R,8S)-α,5-Dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-1,7-dioxaspiro[5.5]undec-10-ene-2-propanoic acid
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (αR,2S,5R,6R,8S)-
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, (αR,2S,5R,6R,8S)-
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[1-methyl-3-[octahydro-8'-hydroxy-6'-[1-hydroxy-3-(3-methyl-1,7-dioxaspiro[5.5]undec-2-yl)butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, [2'R-[2'α[R*[1R*[2S*(R*),5R*,6R*,8S*],2E]],4'aβ,6'β[1S*,3S*(2S*,3R*,6S*)],8'α,8'aα]]-
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[1-methyl-3-[octahydro-8′-hydroxy-6′-[1-hydroxy-3-(3-methyl-1,7-dioxaspiro[5.5]undec-2-yl)butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, [2′R-[2′α[R*[1R*[2S*(R*),5R*,6R*,8S*],2E]],4′aβ,6′β[1S*,3S*(2S*,3R*,6S*)],8′α,8′aα]]-
- 1,7-Dioxaspiro[5.5]undecane, acanthifolicin deriv.
- 35-Demethyl-DTX 1
- 35-Demethyldinophysistoxin 1
- Acanthifolicin, 9,10-deepithio-9,10-didehydro-
- Nsc 677083
- Okadaic acid
- Spiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran], acanthifolicin deriv.
- (2R)-2-hydroxy-3-[(2S,5R,6R,8S)-5-hydroxy-8-{(2R,3E)-4-[(2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl}-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-methylpropanoic acid
- 78111-17-8
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, alpha,5-dihydroxy-alpha,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4a'R,5R,6'S,8'R,8a'S)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (alphaR,2S,5R,6R,8S)-
- OKADAIC ACID, 25 UG*
- 9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIOFOLICIN
- Okadaic acid, free acid >98%
- Okadic acid
- OA
- OKADAIC ACID >95% PROTEIN PHOSPHATASE I
- 1,7-Dioxaspiro5.5undec-10-ene-2-propanoic acid, .alpha.,5-dihydroxy-.alpha.,10-dimethyl-8-(1R,2E)-1-methyl-3-(2R,4aR,5R,6S,8R,8aS)-octahydro-8-hydroxy-6-(1S,3S)-1-hydroxy-3-(2S,3R,6S)-3-methyl-1,7-dioxaspiro5.5undec-2-ylbutyl-7-methylenespirofuran-2(3H),2
- 9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIFOLICIN
- OKADAIC ACID FREE ACID
- Okadaic acid,97%
- OKADAICACID,HIGHPURITY
- 9,10-deepithio-9,10-didehydro-acanthifolici
- OKADAIC ACID AMMONIUM SALT WATER-SOLUBLE ANALOG
- OKADAIC ACID, 98+%
- OKADAIC ACID, PROROCENTRUM CONCAVUM
- Ocadaic Acid
- HALOCHONDRINE A
- Okadaic acid from Prorocentrum concavum,OA
- Okadaic acid 35-Demethyl-DTX 1 NSC 677083 35-Demethyldinophysistoxin 1
- OKADAIC ACID SODIUM SALT 98+%
- Blue mussel, homogenized (Okadaic acid)
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoicacid, a,5-dihydroxy-a,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(
- OKADAIC ACID FROM PROROCENTRUM SP.
- 9,45-Seco-10-demercapto-9,10-didehydroacanthifolicin
- Okadaicacid,Prorocentrumconcavum,highpurity
- Weitere Synonyme anzeigen
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8 Produkte.
Okadaic acid, 98%
CAS:Okadaic acid, is used as an activator of PKC and inhibitor of PP1 and PP2A phosphatases. The hydrophobic backbone of okadaic acid enables it to enter cells where it stimulates intracellular protein phosphorylation. It mimics the effects of insulin, enhances transmitter release at neuromuscular junctFormel:C44H68O13Reinheit:98%Farbe und Form:White, SolidMolekulargewicht:805.02Okadaic acid, Prorocentrum concavum, high purity
CAS:Formel:C44H68O13Reinheit:>98%Molekulargewicht:805.015Okadaic acid
CAS:Formel:C44H68O13Reinheit:≥ 97.0%Farbe und Form:White crystalline powder or solidMolekulargewicht:805.02Okadaic acid, free acid
CAS:Okadaic acid, free acidFormel:C44H68O13Reinheit:>98%Farbe und Form: white lyophilized solidMolekulargewicht:805.00g/molOkadaic acid
CAS:Okadaic acid, a polyether marine toxin, is a highly potent and selective protein phosphatase (PP) inhibitor.Formel:C44H68O13Reinheit:98%Farbe und Form:White Crystals Or PowderMolekulargewicht:805Ref: TM-T16381
100μg (124.2μM*1mL in Ethanol)414,00€25μg (124.2μM*250μL in Ethanol)180,00€50μg (124.2μM*500μL in Ethanol)270,00€Okadaic Acid
CAS:Applications Okadaic acid is a widely distributed marine toxin produced by several phytoplanktonic species and responsible for diarrheic shellfish poisoning in humans. At the molecular level, Okadaic acid is a potent and specific inhibitor of various types of serine/threonine protein phosphatases. Due to this enzymatic inhibition, Okadaic acid was reported to induce numerous alterations in relevant cellular physiological processes, including metabolic pathways such as glucose uptake, lipolysis and glycolysis, heme metabolism and glycogen and protein synthesis. OA. EU regulated marine toxin.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Valdiglesia, V., et al.: J. Toxicol. Enviro. Health., 75, 844 (2012); Kamat, P.K., et al.: Life. Sci., 90, 713 (2012); Valdiglesias, V., et al.: BMC. Genomics., 13, 46 (2012);Formel:C44H68O13Farbe und Form:NeatMolekulargewicht:805.00Okadaic acid
CAS:Inhibitor of PP1 and PP2A protein phosphatasesFormel:C44H68O13Reinheit:Min. 95%Molekulargewicht:805 g/mol
