CAS 9087-70-1

Pankreatischer Trypsin-Inhibitor

Beschreibung:

Pankreatischer Trypsin-Inhibitor (PTI) ist ein Protein, das eine entscheidende Rolle bei der Regulierung von Verdauungsenzymen spielt, insbesondere von Trypsin, das an der Proteinverdauung beteiligt ist. Es stammt aus der Bauchspeicheldrüse und ist bekannt für seine Fähigkeit, die Aktivität von Trypsin zu hemmen, wodurch eine übermäßige Proteolyse im Verdauungssystem verhindert wird. PTI zeichnet sich durch seine relativ kleine Größe aus, die typischerweise aus etwa 58 Aminosäuren besteht, und es weist eine kompakte, stabile Struktur auf, die resistent gegen Denaturierung ist. Der Inhibitor funktioniert durch einen kompetitiven Mechanismus, indem er an die aktive Stelle von Trypsin bindet und den Zugang zum Substrat blockiert. Diese Eigenschaft macht PTI zu einem wertvollen Werkzeug in der biochemischen Forschung und in potenziellen therapeutischen Anwendungen, insbesondere in Situationen, in denen die Aktivität von Proteasen kontrolliert werden muss. Darüber hinaus wurde PTI auf seine potenzielle Rolle in verschiedenen physiologischen Prozessen und seine Auswirkungen auf Krankheiten im Zusammenhang mit der Dysregulation von Proteasen untersucht. Seine CAS-Nummer, 9087-70-1, wird zur Identifizierung in chemischen Datenbanken und regulatorischen Kontexten verwendet.

Formel: Unspecified

Synonyme:

• Antikrein
• Antilysin
• Antilysine
• Antiprovir
• Aprostat
• Aprotinin
• Aprotinin,bovine lung
• Aprotinin,recombinant E.coli
• BPTI trypsin inhibitor
• Basic pancreatic trypsin inhibitor
• Bayer A 128
• Bovine basic pancreatic trypsin inhibitor
• Bovine pancreatic trypsin inhibitor
• Bovine trypsin inhibitor
• Bpti
• Fosten
• Inhibidor De Tripsina, Pancreatica Basica
• Inhibiteur De La Trypsine Pancreatique, Basique
• Kallikrein-trypsin inactivator
• Kiker 52G
• Kir Richter
• Kunitz pancreatic trypsin inhibitor
• Kunitz protease inhibitor
• Kunitz trypsin inhibitor
• Kunitz-type inhibitor
• Kunitz-type proteinase inhibitor
• Kunitz-type trypsin inhibitor
• Onquinin
• Pancreatic basic trypsin inhibitor
• Pancreatic trypsin inhibitor
• Pancreatic trypsin inhibitor (Kunitz)
• Protease inhibitor, Kunitz type
• Recombinant aprotinin,from E.coli
• Repulson
• Rp 9921
• Trasuylol
• Trasylol
• Trazinin
• Triazinin
• Trypsin Inhibitor
• Trypsin Inhibitor, pankreatisch basisch
• Trypsin inhibitor, Trasylol
• Trypsin-kallikrein inhibitor (Kunitz)
• Zymofren
• Trypsin inhibitor, pancreatic basic
• APROTININ-AGAROSE
• Anti-Acetylated Lysine antibody produced in rabbit
• basicpancreatictrypsininhibitor
• trypsin-kallikreininhibitor(kunitz)
• aprotininfrombovinelung
• Anti-Acetylated Lysine:HRP
• riker52g
• pancreatictrypsininhibitor(kunitz)
• Kunity Trypsin Inhibitor of Aprotinium
• APROTININ FROM BOVINE LUNGAFFINITY PURIF IED
• Aids-043659
• H-ARG-PRO-ASP-PHE-CYS-LEU-GLU-PRO-PRO-TYR-THR-GLY-PRO-CYS-LYS-ALA-ARG-ILE-ILE-ARG-TYR-PHE-TYR-ASN-ALA-LYS-ALA-GLY-LEU-CYS-GLN-THR-PHE-VAL-TYR-GLY-GLY-CYS-ARG-ALA-LYS-ARG-ASN-ASN-PHE-LYS-SER-ALA-GLU-ASP-CYS-MET-ARG-THR-CYS-GLY-GLY-ALA-OH
• pancreatictrypsininhibitor
• APROTININ FROM BOVINE LUNG CELL CULTURE TESTED
• APROTININ FROM BOVINE LUNG, ~8000 U/MG P ROTEIN
• Aprotinin(Trypsin Inhibitor)
• Monoclonal Anti-Acetylated Lysine antibody produced in mouse
• TRYPSIN INHIBITOR (BASIC)
• Aprotinin, lyophil.
• Aids043659
• APROTININ, BOVINE LUNG FOR GELFILTRATION CHROMATOG
• trypsininhibitor,pancreaticbasic
• Protease inhibitor
• APROTININ, BOVINE AGAROSE CONJUGATE
• pancreaticbasictrypsininhibitor
• BPI, BPTI, Basic Protease Inhibitor, Pancreatic Trypsin Inhibitor
• APROTININ, BOVINE, RECOMBINANT
• EC: 3.4.21.9
• Anti-Acetylated Lysine-Biotin antibody produced in rabbit
• APROTININ, BOVINE
• PROTEASE INHIBITOR, BOVINE LUNG
• RecoMbinant aprotinin
• Aprotinin from bovine lung,Trypsin inhibitor (basic)
• EZNA KIT ENDO-FREE PLASMID GIGA
• Anti-Acetylated Lysine-Peroxidase antibody produced in rabbit
• Aprotinin from bovine lung, ca. 140 U/mg
• kirrichter
• bayera-128
• TRYPSIN INHIBITOR, BOVINE LUNG
• Anti-Acetylated Lysine: Biotin
• APROTININ FROM BOVINE LUNG, LYOPH.,~7000 U/MG*
• APROTININ-AGAROSE FROM BOVINE LUNG
• Aprotinin solution
• Aprotinin from bovine lung, >=5400 KIU/mg
• kallikrein-trypsininactivator
• Antilysi.
• TRYPSIN INHIBITOR, PANCREAS TYPE
• Rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga

Aprotinin from Bovine Lung

CAS: 9087-70-1

Farbe und Form: White to Light yellow powder to crystal

Ref: 3B-A3549

Aprotinin

CAS: 9087-70-1

Aprotinin (BPTI), a widely used serine protease inhibitor. Bachem’s aprotinin is a synthetic product and is not derived from bovine origin.

Formel: C₂₈₄H₄₃₂N₈₄O₇₉S₇

Reinheit: 99.5%

Farbe und Form: White

Molekulargewicht: 6511.53

Ref: 01-4035911

APROTININ FOR SYSTEM SUITABILITY CRS

CAS: 9087-70-1

APROTININ FOR SYSTEM SUITABILITY CRS

Formel: C₂₀H₂₇BrN₂O₂

Molekulargewicht: 407.3446

Ref: 41-Y0001154

APROTININ SOLUTION BRP

CAS: 9087-70-1

APROTININ SOLUTION BRP

Formel: C₂₀H₂₇BrN₂O₂

Molekulargewicht: 407.3446

Ref: 41-A1250000

Aprotinin

CAS: 9087-70-1

Aprotinin (Traskolan) is a broad-spectrum serine protease (BPTI) inhibitor. Aprotinin is an antifibrinolytic agent. Cost-effective and quality-assured.

Formel: C₂₈₄H₄₃₂N₈₄O₇₉S₇

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 6511.51

Ref: TM-T3359

Aprotinin

CAS: 9087-70-1

Aprotinin

Formel: C₂₈₄H₄₃₂N₈₄O₇₉S₇

Farbe und Form: off-white powder

Molekulargewicht: 6507.04138

Ref: 54-BIMI2132

Aprotinin

CAS: 9087-70-1

Formel: C₂₈₄H₄₃₂N₈₄O₇₉S₇

Molekulargewicht: 6511.51

Ref: 4Z-PA-398001

Aprotinin

CAS: 9087-70-1

Formel: C₂₈₄H₄₃₂N₈₄O₇₉S₇

Reinheit: ≥ 5400KIU/mg (dried basis)

Farbe und Form: White, off-white or pale yellow crystalline powder

Molekulargewicht: 6511.52

Ref: 7W-GP2268

Aprotinin Hydrochloride

CAS: 9087-70-1

Applications Aprotinin is used in cardiac surgery to minimize bleeding and reduce exposure to blood products.
References Mangano, D. et al.: New Eng. J. Med., 354, 353 (2006); Fergusson, D. et al.: New. Eng. J. Med., 358, 2319 (2008);

Formel: C₂₈₄H₄₃₂N₈₄O₇₉S₇·x(ClH)

Farbe und Form: White Solid

Molekulargewicht: 6511.51(free amine)

Ref: TR-A735430

Aprotinin

CAS: 9087-70-1

Aprotinin is a polypeptide protease inhibitor, which is extracted from bovine lung tissue, possessing antifibrinolytic properties. It works by forming reversible stoichiometric complexes with several serine proteases, including trypsin, chymotrypsin, and plasmin, which are involved in the degradation of fibrin. Through inhibition of these proteases, it reduces the breakdown of fibrin clots, thereby exhibiting a hemostatic effect.Aprotinin is primarily used during surgical procedures to minimize bleeding and the need for blood transfusions. It is particularly valuable in cardiopulmonary bypass surgery, where excessive bleeding can be a significant complication. By stabilizing clots and protecting against excessive fibrinolysis, aprotinin aids in maintaining hemostasis and improving outcomes in complex surgical contexts. Scientists continue to explore its biochemical interactions and therapeutic potential, while safety and efficacy remain key areas of investigation.

Formel: C₂₈₄H₄₃₂N₈₄O₇₉S₇

Reinheit: (%) Reported (%)

Farbe und Form: White Powder

Molekulargewicht: 6,511.45 g/mol

Ref: 3D-FA29632

Aprotinin

CAS: 9087-70-1

Aprotinin is a pharmacological agent that inhibits the activity of enzymes such as plasmin, kallikrein, and trypsin. It is used to prevent or reduce the severity of ischemia-reperfusion injury in heart surgery. Aprotinin also inhibits platelet aggregation and promotes blood coagulation. The drug has been shown to inhibit the activity of x-ray crystallographic inhibitor molecules that are involved in intermolecular hydrogen bonding and multivariate logistic regression. Aprotinin has been shown to have effects on eosinophil cationic protein (ECP), which may be related to its anti-inflammatory properties.

Formel: C₂₈₄H₄₃₂N₈₄O₇₉S₇

Reinheit: Min. 95%

Molekulargewicht: 6,511.53 g/mol

Ref: 3D-IAT-3830-PI

Aprotinin ex. Bovine Lung, 3-8 TIU/mg powder

CAS: 9087-70-1

Farbe und Form: White, Powder

Ref: SR-62179

Trypsin inhibitor, pancreatic basic

CAS: 9087-70-1

Formel: C₂₈₄H₃₂₀N₈₄O₇₉S₇

Molekulargewicht: 6398.55

Ref: IN-DA00ILH7