CAS 910292-40-9

Myrothecine A

CAS: 910292-40-9

Myrothecine A is a potent kinase inhibitor that has shown promising results in anticancer research. It is an analog of the natural compound myrocin B, which is found in the Chinese medicinal herb Myrothecium verrucaria. Myrothecine A has been found to inhibit multiple kinases involved in cancer cell growth and survival, leading to apoptosis and tumor regression. This compound has also been shown to be effective against a variety of human cancer cell lines, including breast, lung, and colon cancer. Additionally, Myrothecine A has been detected in urine samples of individuals consuming contaminated food or water sources. The potential of this compound as an anticancer agent makes it an exciting area of research for future treatments.

Formel: C₂₉H₃₈O₁₀

Reinheit: Min. 95%

Molekulargewicht: 546.6 g/mol

Ref: 3D-KLB29240

Myrothecine A

CAS: 910292-40-9

Myrothecine A, a trichothecene mycotoxin discovered in M. roridum, exhibits anticancer properties. It effectively inhibits the proliferation of various cancer cell lines, specifically A549, MCF-7, HepG2, and SMMC-7721, with IC50 values of 95, 70, 60, and 25 µM, respectively. At a concentration of 50 µM, Myrothecine A induces G1 cell cycle arrest in HepG2 cells and promotes apoptosis in SMMC-7721 cells by elevating levels of Bax and cleaved caspase-3, -5, and -8.

Formel: C₂₉H₃₈O₁₀

Farbe und Form: Solid

Molekulargewicht: 546.61

Ref: TM-T85069