CAS 914934-02-4

2-Hydroxy Estradiol 1-N3-Adenine

Kontrolliertes Produkt

CAS: 914934-02-4

Applications 2-Hydroxy Estradiol 1-N3-Adenine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. The N3Ade depurinating adducts could serve as biomarkers to predict the risk of breast cancer.
References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002), Paula, M. et al.: J Steroid Biochem. Mol. Biol., 101, 204 (2006);

Formel: C₂₃H₂₇N₅O₃

Farbe und Form: Neat

Molekulargewicht: 421.492

Ref: TR-H942103