CAS 925902-48-3

(S)-2-(2-Fluoro-[1,1'-biphenyl]-4-yl)propanoic (Isobutyl Carbonic) Anhydride

Kontrolliertes Produkt

CAS: 925902-48-3

Applications (S)-2-(2-Fluoro-[1,1'-biphenyl]-4-yl)propanoic (Isobutyl Carbonic) Anhydride is an intermediate in the synthesis of Rimacalib (R505015), an inhibitor of CaMKII, inhibits VEGF expression in human acute monocytic leukemia cell and SF macrophage obtained from patient with rheumatoid arthritis. This effect may contribute to the anti-arthritic effects of Rimacalib.
References Westra, Johanna., et al.: BMC Musculoskelet Disord.,11 , No pp. given. (2010);

Formel: C₂₀H₂₁FO₄

Farbe und Form: Neat

Molekulargewicht: 344.377

Ref: TR-F925905