CAS 94790-37-1

1-[Bis(dimethylamino)methylen]-1H-benzotriazolium hexafluorophosphat(1-) 3-oxid

Beschreibung:

1-[Bis(dimethylamino)methylen]-1H-benzotriazolium hexafluorophosphat(1-) 3-oxid, allgemein bekannt unter seiner CAS-Nummer 94790-37-1, ist eine chemische Verbindung, die eine Benzotriazol-Einheit aufweist, die für ihre Anwendungen in verschiedenen Bereichen, einschließlich der organischen Synthese und der Materialwissenschaft, bekannt ist. Diese Verbindung zeichnet sich durch ihre einzigartige Struktur aus, die eine bis(dimethylamino)methylen-Gruppe umfasst, die zu ihrer Reaktivität und ihrem Potenzial als nucleophiles Agens beiträgt. Die Anwesenheit des Hexafluorophosphatanions weist auf starke ionische Wechselwirkungen hin, die die Löslichkeit in polaren Lösungsmitteln erhöhen können. Darüber hinaus kann die 3-Oxid-Funktion spezifische elektronische Eigenschaften verleihen, was sie in photochemischen Anwendungen nützlich macht. Die Verbindung wird typischerweise mit Vorsicht behandelt, da sie potenziell toxisch und reaktiv ist, und wird häufig in kontrollierten Laborumgebungen verwendet. Ihre Anwendungen können sich auf Bereiche wie Katalyse, Farbsynthese und als Reagenz in organischen Umwandlungen erstrecken, was ihre Vielseitigkeit in der chemischen Forschung und Entwicklung zeigt.

Formel: C₁₁H₁₆N₅O·F₆P

InChl: InChI=1S/C11H16N5O.F6P/c1-13(2)11(14(3)4)15-9-7-5-6-8-10(9)16(17)12-15;1-7(2,3,4,5)6/h5-8H,1-4H3;/q+1;-1

InChI Key: InChIKey=BSKUEERROYGAFF-UHFFFAOYSA-N

SMILES: C(N(C)C)(N(C)C)=[N+]1C=2C(N(=O)=N1)=CC=CC2.[P+5]([F-])([F-])([F-])([F-])([F-])[F-]

Synonyme:

• 1-[Bis(dimethylamino)methylene]-1H-benzotriazolium hexafluorophosphate(1-) 3-oxide
• 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, hexafluorophosphate(1-) (1:1)
• 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, hexafluorophosphate(1-), 3-oxide
• 2-(1H-Benzotriazole-1-Yl)-1,1,3,3-Tetramethyluronium Hexafluorophosphate
• Hbtu
• N-Hbtu
• N-[(1H-benzotriazol-1-yloxy)(dimethylamino)methylidene]-N-methylmethanaminium hexafluorophosphate
• O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium Hexafluorophosphate
• O-Benzotriazole-N,N,N',N'-tetramethyl-uronium-hexafluoro-phosphate
• O-Benzotriazole-N,N,N',N'-tetramethyl-uronium-hexafluorophosphate

HBTU [Coupling Reagent for Peptide]

CAS: 94790-37-1

Formel: C₁₁H₁₆F₆N₅OP

Reinheit: >98.0%(HPLC)

Farbe und Form: White to Almost white powder to crystal

Molekulargewicht: 379.25

Ref: 3B-B1657

1-(Bis(dimethylamino)methylene)-1H-benzo[d][1,2,3]triazole-1-ium 3-oxide hexafluorophosphate(V), 98%

CAS: 94790-37-1

Formel: C11H16F6N5OP

Farbe und Form: White - Almost white crystal - Powde

Molekulargewicht: 379.24

Ref: BD-BD23222

O-(Benzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium hexafluorophosphate

CAS: 94790-37-1

Formel: C₁₁H₁₆F₆N₅OP

Reinheit: 99.0%

Farbe und Form: Solid, Powder or Crystalline Powder or Solid

Molekulargewicht: 379.247

Ref: 10-F009019

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98%

CAS: 94790-37-1

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate is used as a coupling reagent for solid-phase peptide synthesis. It has been shown to effectively suppress racemization. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. S

Formel: C₁₁H₁₆N₅O

Reinheit: 98%

Farbe und Form: Crystalline powder, White to pale cream

Molekulargewicht: 234.28

Ref: 02-B23597

O-Benzotriazol-1-yl-N,N,N',N'-tetramethyluronium hexafluorophosphate

CAS: 94790-37-1

Formel: C₁₁H₁₆F₆N₅OP

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 379.2418

Ref: IN-DA0035F7

HBTU

CAS: 94790-37-1

Formel: C₁₁H₁₆F₆N₅OP

Reinheit: ≥ 99.0%

Farbe und Form: White to almost white powder or crystals

Molekulargewicht: 379.25

Ref: 7W-GE0864

O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate

CAS: 94790-37-1

O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate

Formel: C₁₁H₁₆N₅O·PF₆

Reinheit: ≥95%

Farbe und Form: white crystals

Molekulargewicht: 379.24181g/mol

Ref: 54-PC6587

HBTU

CAS: 94790-37-1

HBTU is a common reagent used for peptide coupling, which can be employed for amide and ester formation. It is stable, highly reactive, suitable for solid phase and in-solution synthesis. The major advantages of HBTU are high yields, fast reaction times, easy reaction conditions, racemisation control and ease of purification from the water-soluble by-products. HBTU contains both the carbodiimide function and the benzotriazole one, activating the carboxylic acid and forming HOBt in situ. Although HBTU was originally catalogued as uronium salt, X-ray diffraction showed evidence for it to be an aminium salt instead.

Formel: C₁₁H₁₆F₆N₅OP

Reinheit: Min. 99 Area-%

Molekulargewicht: 379.24 g/mol

Ref: 3D-Z-1021

HBTU Reagent

CAS: 94790-37-1

HBTU is a reagent that is used in the synthesis of peptides. It has been shown to have inhibitory properties and stable complexes with ester linkages. HBTU has been shown to have a negative effect on congestive heart disease, which may be due to its ability to bind to receptors and mimic the effects of peptide hormones. This compound is also used as a model system for mitochondrial membrane potential. HBTU binds covalently to the peptide hormone receptor, which slows down the rate of degradation and increases its resistance to proteases. HBTU can also be used as an immunosuppressant drug in animal models of autoimmune diseases by inhibiting T-cell proliferation and cytokine production.

Formel: C₁₁H₁₆N₅OPF₆

Reinheit: Min. 95%

Molekulargewicht: 379.25 g/mol

Ref: 3D-KHB-1065-PI

HBTU

CAS: 94790-37-1

HBTU is a common reagent used for peptide coupling, which can be employed for amide and ester formation. It is stable, highly reactive, suitable for solid phase and in-solution synthesis. The major advantages of HBTU are high yields, fast reaction times, easy reaction conditions, racemisation control and ease of purification from the water-soluble by-products. HBTU contains both the carbodiimide function and the benzotriazole one, activating the carboxylic acid and forming HOBt in situ. Although HBTU was originally catalogued as uronium salt, X-ray diffraction showed evidence for it to be an aminium salt instead.

Formel: C₁₁H₁₆F₆N₅OP

Reinheit: Min. 99 Area-%

Farbe und Form: White Powder

Molekulargewicht: 379.24 g/mol

Ref: 3D-FH07095

HBTU extrapure, 98%

CAS: 94790-37-1

Formel: C₁₁H₁₆F₆N₅OP

Reinheit: min. 98 %

Farbe und Form: White, Crystalline powder

Molekulargewicht: 379.25

Ref: SR-44424

HBTU

CAS: 94790-37-1

Applications HBTU is a coupling reagent used in peptide synthesis. HBTU has been shown to effectively suppress racemization.
References Prasad, K.V.S.R.G. et al.: Int. J. Pharm. Sci. Rev. Res., 8, 108 (2011); Van Den Nest, W, et al.: J. Pep. Sci., 7, 115 (2001);

Formel: C₁₁H₁₆F₆N₅OP

Farbe und Form: White To Off-White

Molekulargewicht: 379.24

Ref: TR-H107500