CAS 951385-68-5

Sildenafil-d8

CAS: 951385-68-5

Formel: C₂₂H₂₂D₈N₆O₄S

Farbe und Form: White To Off-White Solid

Molekulargewicht: 482.63

Ref: 4Z-S-063

Sildenafil-d8 (piperazine-d8)

CAS: 951385-68-5

Reinheit: 99 atom % D

Farbe und Form: White Solid

Molekulargewicht: 482.63

Ref: 3U-D7300

Sildenafil-d8

CAS: 951385-68-5

Sildenafil-d8 is a deuterated compound of Sildenafil. Sildenafil has a CAS number of 139755-83-2. Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor, used to treat erectile dysfunction and reduce symptoms of pulmonary arterial hypertension (PAH).

Formel: C₂₂H₂₂D₈N₆O₄S

Farbe und Form: Solid

Molekulargewicht: 482.63

Ref: TM-TMID-0043

Sildenafil-d8

Kontrolliertes Produkt

CAS: 951385-68-5

Applications Sildenafil-d8 is the labeled analogue of Sildenafil (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor.
References Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996); Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998)

Formel: C₂₂₂H₈H₂₂N₆O₄S

Farbe und Form: White To Off-White

Molekulargewicht: 482.63

Ref: TR-S435003

Sildenafil-d8

Kontrolliertes Produkt

CAS: 951385-68-5

Sildenafil-d8 is a chemical that is used in medicine. It is the 8-deuterated analog of sildenafil. Sildenafil-d8 has been shown to be more potent than sildenafil in inhibiting phosphodiesterase type-5 (PDE5) and to have a longer half-life. This drug has been shown to be effective in the treatment of pulmonary hypertension, which may be due to its ability to relax smooth muscle cells. Sildenafil-d8 can also be used for the treatment of erectile dysfunction, as it inhibits PDE5, an enzyme that degrades cyclic guanosine monophosphate (cGMP). The effects of this drug are dose dependent and are enhanced by the presence of a matrix effect. This drug is extracted from methanol using liquid chromatography with UV detection at 254 nm and mass spectrometry detection at m/z=

Formel: C₂₂H₂₂D₈N₆O₄S

Reinheit: Min. 95%

Molekulargewicht: 482.63 g/mol

Ref: 3D-BNB38568