CAS 97818-83-2

(Z)-1-[4-(2-Chloroethoxyphenyl]-1,2-diphenyl-1-butene

Kontrolliertes Produkt

CAS: 97818-83-2

Applications Intermediate in the prepration of Tamoxifen derivatives.
References Stanciuc, O., et al.: J. Pharm. Sci., 82, 927 (1993), Laios, I., et al.: J. Steroid Biochem. Mol. Biol., 87, 207 (2004),

Formel: C₂₄H₂₃ClO

Farbe und Form: Neat

Molekulargewicht: 362.89

Ref: TR-C365780

(Z)-Chlorolefin-13C6

Kontrolliertes Produkt

CAS: 97818-83-2

Applications (Z)-Chlorolefin-13C6 is an intermediate in the synthesis of Tamoxifen-13C6 (T006002), which is a labeled Tamoxifen; a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells.Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen (H954725) are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-sti
References Sutherland, R., et al.: Nature, 267, 434 (1977); Lerner, L., et al.: Cancer Res., 50, 4177 (1990); Love, R., et al.: J. Clin. Oncol., 20 2559 (2002);

Formel: C₆C₁₈H₂₃ClO

Farbe und Form: Neat

Molekulargewicht: 368.848

Ref: TR-C365781

(E/Z)-1-[4-(2-Chloroethoxyphenyl]-1,2-diphenyl-1-butene

Kontrolliertes Produkt

CAS: 97818-83-2

Applications Intermediate in the prepration of Tamoxifen derivatives.

Formel: C₂₄H₂₃ClO

Farbe und Form: Neat

Molekulargewicht: 362.89

Ref: TR-C365775

(Z)-1-[4-(2-Chloroethoxyphenyl]-1,2-diphenyl-1-butene

CAS: 97818-83-2

Please enquire for more information about (Z)-1-[4-(2-Chloroethoxyphenyl]-1,2-diphenyl-1-butene including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formel: C₂₄H₂₃ClO

Reinheit: Min. 95%

Molekulargewicht: 362.89 g/mol

Ref: 3D-FC20223

Z-Chlorolefine

CAS: 97818-83-2

Formel: C₂₄H₂₃ClO

Molekulargewicht: 362.9

Ref: ST-EA-CP-T40019