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CAS 98796-51-1
:Thymidin, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit]
Beschreibung:
Thymidin, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit], allgemein bekannt unter seiner CAS-Nummer 98796-51-1, ist ein synthetisches Nukleosidderivat, das hauptsächlich im Bereich der Molekularbiologie und Biochemie verwendet wird. Diese Verbindung weist eine Thyminbasis auf, die ein Bestandteil der DNA ist, und ist an den Positionen 5' und 3' modifiziert. Die 5'-Position ist mit einer bis(4-Methoxyphenyl)phenylmethylgruppe substituiert, die ihre Stabilität und Löslichkeit erhöht, während die 3'-Position mit einer Cyanoethylphosphoramiditgruppe modifiziert ist, die entscheidend für ihre Rolle in der Oligonukleotidsynthese ist. Das Vorhandensein der Phosphoramiditgruppe ermöglicht die Einbindung dieser Verbindung in DNA-Stränge während der Festphasen-Synthese, was sie wertvoll für die Herstellung von maßgeschneiderten Oligonukleotiden für Forschungs- und therapeutische Anwendungen macht. Ihre strukturellen Eigenschaften tragen zu ihrer Reaktivität und Nützlichkeit in verschiedenen biochemischen Prozessen bei, insbesondere bei der Synthese von DNA- und RNA-Analoga.
Formel:C40H49N4O8P
InChl:InChI=1/C10H14N2O5.C3H6N2O2P/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8;1-3(2-4)7-8(5)6/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16);3H,5H2,1H3/q;-1/t6-,7+,8+;/m0./s1
InChI Key:InChIKey=UNOTXUFIWPRZJX-CEXSRUIHSA-N
SMILES:C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)C[C@@H](O1)N2C(=O)NC(=O)C(C)=C2)(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5
Synonyme:- 5'-Dimethoxytrityl-3'-deoxythymidine 2'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
- 5'-O-(4,4'-Dimethoxytrityl)-thymidine-3'-cyanoethyl Phosphoramidite
- 5′-O-(4,4′-Dimethoxytrityl)thymidine 3′-(2-cyanoethyl-N,N-diisopropylphosphoramidite)
- 5′-O-(4,4′-Dimethoxytriyl)thymidine 3′-(2-cyanoethyl)-N,N-diisopropylphosphoramidite
- 5′-O-DMT-thymidine 3′-CE phosphoramidite
- DMT-dT phosphoramidite
- DNA T Phosphoramidite
- DT-CE phosphoramidite
- Deoxythymidine phosphoramidite
- Thymidine phosphoramidite
- Thymidine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- Thymidine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
- dT Phosphoramidite
- DMT-dT Amidite 1g, 60ml vial, 12 Pack
- DMT-dT amidite
- T-CE phosphoramidite
- 5'-DMT-dT phosphoramidite
- 5'-O-(4,4'-Dimethoxytrityl)thymidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite
- thymidine-ce phosphoramidite for*biosearch 8000
- 3'-O-P-5'-O-DMT-2'-DEOXY-THYRIDINE [DT PHOSPHORAMIDITE]
- 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-thymidine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
- DMT-DT AMIDITE 1G AB 12 PACK
- 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-5-methyluridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite
- 5'-O-DMT-2'-deoxythymidine-3'-CE Phosphoramidite
- DMT-dT Amidite 2g, 60ml vial, 12 Pack
- 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYTHYMIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE
- DMT-DT AMIDITE 2G 89 12 PACK
- REF DUPL: dT Phosphoramidite
- 5'-O-[Bis(4-Methoxyphenyl)phenylMethyl]-thyMidine 3'-[2-cyanoethyl N,N-bis(1-Methylethyl)phosphoraMidite]
- 5'-O-Dimethoxytrityl-2'-deoxy-thymidine-3'-O-(2-cyanoethyl)-Phosphoramidite
- N-blocked-5'-O-DMT 3'-CED thymidine phosphoramidite
- DMT-dT-CE-Phosphoramidite
- DMT-DT AMIDITE 10G SINGLE
- (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite
- 5'-O-DMT-N2-isobutyryl-2'-de5'-O-DMT-Thymidine 3'-CE phosphoramidite
- DMT-dT Amidite 6.85g, 6 Pack
- 5'-O-DMT- 2'-Deoxy Thymidine Phosphoramidite
- DMT-DT AMIDITE 5G SINGLE
- DMT-DT AMIDITE 4G 60ML VIAL 12 PACK
- 5′-O-(4,4′-dimethoxytrityl)-2′-deoxythymidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]
- DMT-DT AMIDITE 2G AB 12 PACK
- DMT-dT Pharmadite
- Thymidine-3'-phosphoramidite
- DMT-DT AMIDITE 5G 6 PACK
- DMT-THYMIDINE CED PHOSPHORAMIDITE
- 5''-O-(4,4''-Dimethoxytrityl)-thymidine-3''-N,N-diisopropyl-(2-cyanoethyl)-pho
- DNAT-PHOSPHORAMIDITE
- 5'-O-(DIMETHOXYTRITYL)-THYMIDINE-3'-N,N-DIISOPROPYL(CYANOETHYL)PHOSPHORAMIDITE
- DMT-DT AMIDITE 20G 6 PACK
- Weitere Synonyme anzeigen
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9 Produkte.
DMT-dT Phosphoramidite
CAS:Formel:C40H49N4O8PReinheit:>98.0%(HPLC)Farbe und Form:White to Light yellow powder to crystalMolekulargewicht:744.83T β-Cyanoethyl Phosphoramidite (5'-O-Dimethoxytritylthymidine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormel:C40H49N4O8PFarbe und Form:White PowderMolekulargewicht:744.83Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]
CAS:Formel:C40H49N4O8PReinheit:97%Farbe und Form:SolidMolekulargewicht:744.8128DMT-dT Phosphoramidite
CAS:DMT-dT Phosphoramidite is typically used in the synthesis of DNA.Formel:C40H49N4O8PFarbe und Form:SolidMolekulargewicht:744.815'-O-DMT-thymidine 3'-CE phosphoramidite
CAS:<p>5'-O-DMT-thymidine 3'-CE phosphoramidite is a building block for the introduction of thymidine units into oligonucleotides. 5'-O-DMT-thymidine 3'-CE phosphoramidite is utilised in a broad range of applications, including the synthesis of natural and unnatural DNA and RNA strands. Phosphoramidites are the reagent class of choice for oligonucleotide synthesis as they contain readily removable orthogonal protecting groups and can be produced at reasonable scales. The diisopropylamino leaving group is readily cleaved upon exposure to an azole catalyst allowing for a highly efficient coupling reaction with a free hydroxyl group on the growing oligonucleotide and oxidation of the subsequent phosphite triester, followed by beta-elimination of the cyanoethyl group affords the stable phosphodiester linkage.</p>Formel:C40H49N4O8PReinheit:Min. 98 Area-%Farbe und Form:PowderMolekulargewicht:744.83 g/mol
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