BTK

GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical …

Btk inhibitor 2 (BGB-3111 analog) is a BTK inhibitor.

Tirabrutinib hydrochloride (GS-4059 (hydrochloride)) is a selective and novelBTK with IC50 2.2 nm inhibitor.

MT-802 is an effective BTK degrader based on PROTAC technology (DC50: 1 nM). MT-802 has …

IBT6A is an impurity of Ibrutinib. Ibrutinib is a Btk inhibitor (IC50: 0.5 nM). IBT6A …

Rilzabrutinib (PRN1008) is a reversible covalent, selective and oral active inhibitor of Bruton’s Tyrosine Kinase …

ARQ-531 is a potent and orally active BTK inhibitor with potential antineoplastic activity, with IC50s …

Orelabrutinib (ICP-022) is an orally active and irreversible inhibitor of Bruton's tyrosine kinase (BTK).

(±)-Zanubrutinib ((±)-BGB-3111) is a potent and orally available Bruton's tyrosine kinase (Btk) inhibitor that demonstrates …

Sunvozertinib (DZD9008) is a potent ErbBs and BTK inhibitor and has inhibitory effects on EGFR, …

Cinsebrutinib, a Bruton's tyrosine kinase inhibitor, holds potential for research in cancer treatment.

BTK inhibitor 1 (Compound 27) is a BTK inhibitor (IC50: 0.11 nM) with an inhibitory …

PROTAC BTK Degraders-5 (Compound 3e) is a selective Bruton's tyrosine kinase (BTK) degrader with a …

(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).

BTK-IN-16 is a potential inhibitor of wild-type BTK and C481S mutants.BTK-IN-16 can be used to …

BTK-IN-27 (example 8), a potent BTK inhibitor with an IC50 of 0.2 nM, demonstrates anti-proliferative …

AS-1763 is an orally available and selective BTK inhibitor with an IC50 of 0.85 nM.

BMS-935177 is a reversible BTK inhibitor with IC50 value of 3 nM.

NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S …

Tilfrinib is an effective and selective inhibitor of breast tumor kinase(Brk, IC50 = 3.15 nM) …