Thrombin
Thrombin-Inhibitoren sind Verbindungen, die Thrombin blockieren, ein Enzym, das am Blutgerinnungsprozess beteiligt ist und auch eine Rolle bei der Förderung der Angiogenese spielt. Thrombin kann die Bildung neuer Blutgefäße in Tumoren anregen und so deren Wachstum und Metastasierung unterstützen. Durch die Hemmung von Thrombin können diese Verbindungen die Angiogenese und das Tumorwachstum reduzieren. Thrombin-Inhibitoren sind sowohl in der Krebsforschung als auch bei der Untersuchung von Gefäßerkrankungen von Bedeutung. Bei CymitQuimica bieten wir eine Auswahl hochwertiger Thrombin-Inhibitoren zur Unterstützung Ihrer Forschung in den Bereichen Hämostase, Onkologie und Angiogenese an.
56 Produkte aus dem Bereich "Thrombin" gefunden
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Dabigatran etexilate
CAS:Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation.Formel:C34H41N7O5Reinheit:98.19% - 99.98%Farbe und Form:White PowderMolekulargewicht:627.73Dabigatran ethyl ester hydrochloride
CAS:Dabigatran prevents blood clots, inhibiting NQO2 and thrombin with IC50 0.8 μM.Formel:C27H30ClN7O3Reinheit:99.65%Farbe und Form:SolidMolekulargewicht:536.03Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated)
CAS:Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is a hirugen-like peptide with greater thrombin affinity than Hirugen, exhibiting a dissociation constant (KFormel:C64H88N10O26SReinheit:98%Farbe und Form:SolidMolekulargewicht:1445.5Acetyl-Hirudin (54-65) (sulfated)
CAS:Acetyl-Hirudin (54-65) (sulfated) binds thrombin-rHCII(L444R), blocking rHCII's N-terminal/thrombin exosite I interaction, stabilizing the complex.Formel:C68H95N13O29SFarbe und Form:SolidMolekulargewicht:1590.63Thrombin inhibitor 13
Thrombin inhibitor 13 (Compound 13a) acts as a covalent reversible inhibitor of thrombin (thrombin, FIIa) with an IC50 of 0.7 nM. This compound prolongs activated partial thromboplastin time (aPTT) and prothrombin time (PT), demonstrating both antithrombotic and anticoagulant properties.Formel:C16H17ClN6OSFarbe und Form:SolidMolekulargewicht:376.864Hirullin P18
CAS:Hirullin P18 is a potent thrombin inhibitor with anticoagulant properties [1].Formel:C68H96N14O29Reinheit:98%Farbe und Form:SolidMolekulargewicht:1573.57Thrombin (MW 37kDa)
CAS:Thrombin (MW 37kDa) is a trypsin-like allosteric serine protease.Reinheit:98%Farbe und Form:SolidMolekulargewicht:37kDaH-Gly-Arg-pNA dihydrochloride
CAS:H-Gly-Arg-pNA 2HCl, a peptide, binds 1,2 thrombin; colorimetric quantification at 405 nm indicates thrombin activity.Formel:C14H23Cl2N7O4Reinheit:99.14%Farbe und Form:SolidMolekulargewicht:424.28Hirudin (54-65) (TFA)
Hirudin (54-65) TFA, a segment of the 65-amino-acid protein Hirudin, exhibits anticoagulant properties [1].Farbe und Form:Odour SolidKnob A peptide GPRPFPAC
CAS:Knob A peptide GPRPFPAC is a fibrin knob peptide. The PEGylated form of Knob A peptide GPRPFPAC exhibits enhanced anticoagulant activity.Formel:C38H57N11O9SFarbe und Form:SolidMolekulargewicht:843.99Fibrinopeptide B, human
CAS:Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer.Formel:C66H93N19O25Reinheit:98%Farbe und Form:SolidMolekulargewicht:1552.56PM 102
CAS:Peptide that reverses the anticoagulant effect of heparin. Potently binds heparin (Kd = 36 nM in vitro).Formel:C235H425N111O64Reinheit:98%Farbe und Form:SolidMolekulargewicht:5830Thrombin receptor peptide ligand
CAS:Thrombin receptor peptide ligand, a thrombin receptor antagonist, serves as an antithrombotic agent [1].Formel:C33H54N10O8Reinheit:98%Farbe und Form:SolidMolekulargewicht:718.84TFLLRNPNDK-NH2
CAS:TFLLRNPNDK-NH2 is a biologically active peptide and a thrombin receptor activating peptide (TRAP).Formel:C54H89N17O15Reinheit:98%Farbe und Form:SolidMolekulargewicht:1216.39Ichorcumab
CAS:Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.
Farbe und Form:LiquidSulodexide
CAS:Sulodexide is an orally administered combination of glycosaminoglycans, consisting of low molecular weight heparin (80%) and dermatan sulfate (20%). It demonstrates antithrombotic properties by interacting with antithrombin III (AT III) and heparin cofactor II (HC II), and by inhibiting thrombin formation. Additionally, sulodexide enhances profibrinolytic activity by releasing tissue plasminogen activator (tPA). It also offers endothelial protection, possesses anti-inflammatory effects, and alleviates chronic venous disease.Farbe und Form:SolidPlatelet aggregation-IN-1
Platelet aggregation-IN-1 (Compound 10e) acts as an inhibitor of platelet aggregation and can achieve complete (100%) inhibition of thrombin-induced platelet aggregation at a concentration of 50 μM.Formel:C18H13N3O4Molekulargewicht:335.09061Fibrinogen-Binding Peptide
CAS:Fibrinogen-binding peptide mimics vitronectin site and activates platelets; thrombin turns it to fibrin.Formel:C25H39N7O8Reinheit:98%Farbe und Form:SolidMolekulargewicht:565.62Protease Inhibitor Library
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;Farbe und Form:Odour SolidRef: TM-L1100
1mgNachfragen30μL*10mM (DMSO)Nachfragen50μL*10mM (DMSO)Nachfragen100μL*10mM (DMSO)Nachfragen250μL*10mM (DMSO)NachfragenHirudin (55-65) (sulfated)
CAS:Hirudin (55-65) (sulfated), a fragment of Hirudin, is a thrombin inhibitor with anticoagulant effects and blood anticoagulant properties.Formel:C64H90N12O27SFarbe und Form:SolidMolekulargewicht:1491.53
