Integrin
Integrin-Inhibitoren zielen auf Integrine ab, eine Familie von Zelloberflächenrezeptoren, die eine entscheidende Rolle bei der Zelladhäsion, Migration und Signaltransduktion spielen. Integrine sind an der Regulation des Zellzyklus beteiligt, insbesondere an Prozessen wie Zellteilung und Differenzierung. Die Hemmung von Integrinen kann diese Prozesse stören, was zu einem Zellzyklusarrest und Apoptose führt, wodurch diese Inhibitoren wertvolle Werkzeuge in der Krebsforschung und der Untersuchung von Metastasen sind. Bei CymitQuimica bieten wir eine breite Palette hochwertiger Integrin-Inhibitoren zur Unterstützung Ihrer Forschung in den Bereichen Zellzyklusregulation, Krebsbiologie und therapeutische Entwicklung an.
224 Produkte aus dem Bereich "Integrin" gefunden
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Abituzumab
CAS:<p>Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.</p>Reinheit:>95%Farbe und Form:LiquidTidutamab
CAS:<p>Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T cell binding domain (CD3).</p>Reinheit:97.9% (SDS-PAGE); 97.8% (SEC-HPLC) - 97.9% (SDS-PAGE); 97.8% (SEC-HPLC)Farbe und Form:LiquidOrbofiban TFA
CAS:<p>Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronary</p>Formel:C19H24F3N5O6Reinheit:97.21% - 98.72%Farbe und Form:SolidMolekulargewicht:475.42RWJ 50271
CAS:<p>RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.</p>Formel:C18H17F3N4O2SReinheit:99.09%Farbe und Form:SolidMolekulargewicht:410.41Vedolizumab
CAS:<p>Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.</p>Reinheit:SDS-PAGE:98.4%;SEC-HPLC:99.1%Farbe und Form:LiquidMolekulargewicht:146.80 kDaOtelixizumab
CAS:<p>Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.</p>Reinheit:>95%Farbe und Form:LiquidCibisatamab
CAS:<p>Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.</p>Reinheit:SDS-PAGE:99.1%;SEC-HPLC:96.5%Farbe und Form:LiquidMolekulargewicht:191.1 kDaForalumab
CAS:<p>Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.</p>Reinheit:96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Farbe und Form:LiquidATN-161 trifluoroacetate salt
CAS:<p>ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.</p>Formel:C25H36F3N9O10SReinheit:98% - 99.98%Farbe und Form:SolidMolekulargewicht:711.67Tadocizumab
CAS:<p>Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.</p>Reinheit:97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)Farbe und Form:LiquidBersanlimab
CAS:<p>Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.</p>Reinheit:> 95% - > 95%Farbe und Form:LiquidMolekulargewicht:144.22 kDaAbciximab
CAS:<p>Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.</p>Reinheit:SDS-PAGE:95.2%;SEC-HPLC:95.9%Farbe und Form:LiquidMolekulargewicht:95.18 kDaElarofiban TFA
CAS:<p>Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.</p>Formel:C26H34F6N4O8Reinheit:99.08%Farbe und Form:SoildMolekulargewicht:644.56Abrilumab
CAS:<p>Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.</p>Reinheit:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Farbe und Form:LiquidEfalizumab
CAS:<p>Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.</p>Reinheit:SDS-PAGE:95% SEC-HPLC:98.77%Farbe und Form:LiquidMolekulargewicht:146.14 kDaTeplizumab
CAS:<p>Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.</p>Reinheit:SDS-PAGE:95.8%;SEC-HPLC:99.7%Farbe und Form:LiquidMolekulargewicht:145.79 kDaAB-3PRGD2
CAS:<p>AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.</p>Formel:C137H215IN30O45SFarbe und Form:SolidMolekulargewicht:3161.32LDV FITC
CAS:<p>fluorescent ligand that binds to the α4β1 integrin (VLA-4)</p>Formel:C69H81N11O17SReinheit:98%Farbe und Form:SolidMolekulargewicht:1368.53Ac-MRGDH-NH2
<p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>Formel:C25H41N11O8SFarbe und Form:SolidMolekulargewicht:655.727SMS 121
CAS:<p>SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.</p>Formel:C20H21NO5Reinheit:98.29%Farbe und Form:SoildMolekulargewicht:355.38
