c-Myc
c-Myc-Inhibitoren zielen auf das c-Myc-Protein ab, einen Transkriptionsfaktor, der eine zentrale Rolle beim Zellwachstum, der Proliferation und der Apoptose spielt. c-Myc reguliert die Expression zahlreicher Gene, die am Zellzyklus beteiligt sind, und ist in verschiedenen Krebsarten häufig überexprimiert, was zu unkontrollierter Zellproliferation und Tumorwachstum führt. Die Hemmung von c-Myc kann diese Prozesse stören und zu Zellzyklusarrest und Apoptose in Krebszellen führen. c-Myc-Inhibitoren sind wichtige Werkzeuge in der Krebsforschung und der therapeutischen Entwicklung. Bei CymitQuimica bieten wir eine breite Palette hochwertiger c-Myc-Inhibitoren zur Unterstützung Ihrer Forschung in den Bereichen Onkologie, Zellzyklusregulation und Transkriptionskontrolle an.
69 Produkte aus dem Bereich "c-Myc" gefunden
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Ceramides Mixture
CAS:<p>Ceramides Mixture: endogenous, regulates cell cycle, growth, and telomerase activity, with hydroxy/non-hydroxy fatty acids.</p>Formel:C36H71NO4Reinheit:98%Farbe und Form:SolidMolekulargewicht:581.967FIDAS-5
CAS:<p>FIDAS-5 is an orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. Cost-effective and quality-assured.</p>Formel:C15H13ClFNReinheit:97.66% - 98.3%Farbe und Form:SolidMolekulargewicht:261.72Eragidomide
CAS:<p>Eragidomide (Cereblon modulator 1) is a CRBN E3 ligase modulator, specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.</p>Formel:C22H18ClF2N3O4Reinheit:97.51% - 99.63%Farbe und Form:SolidMolekulargewicht:461.85MYCi361
CAS:<p>MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).</p>Formel:C26H16ClF9N2O2Reinheit:99.52%Farbe und Form:SolidMolekulargewicht:594.86MYCMI-6
CAS:<p>MYCMI-6 inhibits MYC:MAX, reduces tumor growth, triggers apoptosis, minimal side effects.</p>Formel:C20H19N7OReinheit:99.23%Farbe und Form:SolidMolekulargewicht:373.41MYCi975
CAS:<p>MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.</p>Formel:C25H16Cl2F6N2O2Reinheit:99.3% - 99.82%Farbe und Form:SolidMolekulargewicht:561.3Saxagliptin hydrate
CAS:<p>Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).</p>Formel:C18H25N3O2·H2OReinheit:99.52%Farbe und Form:SolidMolekulargewicht:333.43KJ Pyr 9
CAS:<p>KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).</p>Formel:C22H15N3O4Reinheit:99.56% - ≥98%Farbe und Form:SolidMolekulargewicht:385.37FIDAS-3
CAS:<p>FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities</p>Formel:C16H15F2NReinheit:97.75%Farbe und Form:SolidMolekulargewicht:259.29APTO-253
CAS:<p>APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells.</p>Formel:C22H14FN5Reinheit:98.73%Farbe und Form:SolidMolekulargewicht:367.38c-Myc inhibitor 10
CAS:<p>c-Myc inhibitor 10 enhances cell potency with improved permeability from methylated morpholine nitrogen.</p>Formel:C28H38N6O3Farbe und Form:SolidMolekulargewicht:506.64c-Myc inhibitor 5
<p>DA3: Fluorescent c-Myc inhibitor, targets c-MYC G-quadruplex (K D 16 μM), selective, suppresses c-MYC expression.</p>Formel:C30H46N12Farbe und Form:SolidMolekulargewicht:574.77Anti-c-myc Antibody (9E10)
<p>Anti-c-myc Antibody (9E10) is a chimeric mouse IgG1 antibody targeting human c-myc.</p>Farbe und Form:Odour LiquidAnticancer agent 263
<p>Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.</p>Formel:C13H20N2O6Farbe und Form:SolidMolekulargewicht:300.308Cotylenin A
CAS:<p>Cotylenin A is a phenanthraquinone compound that synergistically works with vitamin K2 to induce monocyte differentiation and growth arrest. It also inhibits c-Myc expression while inducing cyclin G2 expression in human leukemia HL-60 cells. Cotylenin A is applicable in acute myeloid leukemia research.</p>Formel:C33H50O11Farbe und Form:SolidMolekulargewicht:622.744H122
<p>H122 is a TEADPROTAC degrader effective in degrading TEAD1 with a DC50 of 3 nM, and it shows strong affinity for TEAD2, TEAD3, and TEAD4 with Ki values of 2.0, 3.6, and 1.6 nM, respectively. H122 also downregulates Myc expression and inhibits the growth of MSTO-211H and NCI-H226 cells, with IC50 values of 21.3 nM and 0.6 nM, respectively, demonstrating antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligaseCereblon)</p>Formel:C45H45ClFN5O8Farbe und Form:SolidMolekulargewicht:838.319Methylcarbamyl PAF C-8
<p>Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.</p>Farbe und Form:Odour SolidRA-V
<p>RA-V is a natural product that can be used as a reference standard.</p>Formel:C160H202N24O41Farbe und Form:SolidMolekulargewicht:3117.5VGN50
<p>VGN50 is a bioactive molecule that mimics the function of K-Rta, capable of downregulating MYC-mediated gene transcription. VGN50 exhibits antitumor activity.</p>Formel:C121H218N46O32Molekulargewicht:2827.68453MYC-IN-2
CAS:<p>MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research.</p>Formel:C25H17N3O2SFarbe und Form:SolidMolekulargewicht:423.49
