c-Myc
c-Myc-Inhibitoren zielen auf das c-Myc-Protein ab, einen Transkriptionsfaktor, der eine zentrale Rolle beim Zellwachstum, der Proliferation und der Apoptose spielt. c-Myc reguliert die Expression zahlreicher Gene, die am Zellzyklus beteiligt sind, und ist in verschiedenen Krebsarten häufig überexprimiert, was zu unkontrollierter Zellproliferation und Tumorwachstum führt. Die Hemmung von c-Myc kann diese Prozesse stören und zu Zellzyklusarrest und Apoptose in Krebszellen führen. c-Myc-Inhibitoren sind wichtige Werkzeuge in der Krebsforschung und der therapeutischen Entwicklung. Bei CymitQuimica bieten wir eine breite Palette hochwertiger c-Myc-Inhibitoren zur Unterstützung Ihrer Forschung in den Bereichen Onkologie, Zellzyklusregulation und Transkriptionskontrolle an.
76 Produkte aus dem Bereich "c-Myc" gefunden
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MYCi975
CAS:MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.Formel:C25H16Cl2F6N2O2Reinheit:99.3% - 99.82%Farbe und Form:SolidMolekulargewicht:561.3FIDAS-5
CAS:FIDAS-5 is an orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. Cost-effective and quality-assured.Formel:C15H13ClFNReinheit:98.3% - 99.17%Farbe und Form:SolidMolekulargewicht:261.72Ref: TM-T11285
1mg59,00€2mg85,00€5mg116,00€10mg187,00€25mg331,00€50mg512,00€100mg740,00€500mg1.415,00€Eragidomide
CAS:Eragidomide (Cereblon modulator 1) is a CRBN E3 ligase modulator, specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.Formel:C22H18ClF2N3O4Reinheit:97.51% - 99.63%Farbe und Form:SolidMolekulargewicht:461.85Ref: TM-T10765
1mg38,00€5mg82,00€10mg133,00€25mg269,00€50mg442,00€100mg595,00€200mg802,00€1mL*10mM (DMSO)84,00€Saxagliptin hydrate
CAS:Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).Formel:C18H25N3O2·H2OReinheit:99.52%Farbe und Form:SolidMolekulargewicht:333.43MYCi361
CAS:MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).Formel:C26H16ClF9N2O2Reinheit:99.52%Farbe und Form:SolidMolekulargewicht:594.86Ceramides Mixture
CAS:Ceramides Mixture: endogenous, regulates cell cycle, growth, and telomerase activity, with hydroxy/non-hydroxy fatty acids.Formel:C36H71NO4Reinheit:98%Farbe und Form:SolidMolekulargewicht:581.967MYCMI-6
CAS:MYCMI-6 inhibits MYC:MAX, reduces tumor growth, triggers apoptosis, minimal side effects.Formel:C20H19N7OReinheit:99.23%Farbe und Form:SolidMolekulargewicht:373.41Ref: TM-T12134
1mg71,00€5mg152,00€10mg222,00€25mg358,00€50mg512,00€100mg707,00€200mg973,00€500mg1.431,00€KJ Pyr 9
CAS:KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).Formel:C22H15N3O4Reinheit:99.56% - ≥98%Farbe und Form:SolidMolekulargewicht:385.37Ref: TM-T15665
2mg37,00€5mg54,00€10mg77,00€25mg138,00€50mg264,00€100mg482,00€200mg647,00€500mg1.009,00€1mL*10mM (DMSO)59,00€FIDAS-3
CAS:FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activitiesFormel:C16H15F2NReinheit:97.75%Farbe und Form:SolidMolekulargewicht:259.29Ref: TM-T11284
5mg49,00€10mg73,00€25mg127,00€50mg182,00€100mg264,00€200mg354,00€1mL*10mM (DMSO)48,00€APTO-253
CAS:APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells.Formel:C22H14FN5Reinheit:98.73%Farbe und Form:SolidMolekulargewicht:367.38Ref: TM-T10352
1mg40,00€2mg52,00€5mg75,00€10mg96,00€25mg170,00€50mg255,00€100mg371,00€1mL*10mM (DMSO)84,00€PROTAC MTP3 degrade-1
PROTACMTP3 degrade-1 is a PROTAC degrader for MYC.Formel:C44H38N6O8Farbe und Form:SolidMolekulargewicht:778.27511c-Myc inhibitor 10
CAS:c-Myc inhibitor 10 enhances cell potency with improved permeability from methylated morpholine nitrogen.Formel:C28H38N6O3Farbe und Form:SolidMolekulargewicht:506.64Anticancer agent 263
Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.Formel:C13H20N2O6Farbe und Form:SolidMolekulargewicht:300.308c-Myc inhibitor 7
CAS:c-Myc inhibitor 7 degrades c-MYC, CK1α, GSPT1, IKZF1/2/3 proteins in tumors, for research on related diseases.Formel:C35H30N6O5Farbe und Form:SoildMolekulargewicht:614.65H122
H122 is a TEADPROTAC degrader effective in degrading TEAD1 with a DC50 of 3 nM, and it shows strong affinity for TEAD2, TEAD3, and TEAD4 with Ki values of 2.0, 3.6, and 1.6 nM, respectively. H122 also downregulates Myc expression and inhibits the growth of MSTO-211H and NCI-H226 cells, with IC50 values of 21.3 nM and 0.6 nM, respectively, demonstrating antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligaseCereblon)Formel:C45H45ClFN5O8Farbe und Form:SolidMolekulargewicht:838.319VTX-0811
VTX-0811 is a human IgG4 monoclonal antibody (mAb) that targets PSGL1/CD162. It modulates immune signaling pathways by enhancing TNF-α/NF-κB and chemokine-mediated signaling while reducing oxidative phosphorylation, fatty acid metabolism, and Myc signaling. VTX-0811 increases the proportion of CD8+ T cells among infiltrating T cells and exhibits antitumor activity in humanized mouse PDX models of melanoma.Farbe und Form:Odour LiquidVGN50
VGN50 is a bioactive molecule that mimics the function of K-Rta, capable of downregulating MYC-mediated gene transcription. VGN50 exhibits antitumor activity.Formel:C121H218N46O32Molekulargewicht:2827.68453RA-V
RA-V is a natural product that can be used as a reference standard.Formel:C160H202N24O41Farbe und Form:SolidMolekulargewicht:3117.5c-Myc inhibitor 13
c-Myc inhibitor13 (compound A6) is an inhibitor of c-MYC transcription. It selectively stabilizes c-MYCG4 and inhibits G4-related c-MYC transcription.Formel:C30H39N9OMolekulargewicht:541.32776Methylcarbamyl PAF C-8
Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.Farbe und Form:Odour Solid
