ROR

TMP920 inhibits RORγt binding to the SRC1 peptide (IC50: 0.03 μM). TMP920 is a highly …

Cholesterol (cholesteryl alcohol) is a natural product that is the major sterol in mammals and …

RORγ antagonist 1 (compound 22), a potent derivative of betulinic acid, acts as an antagonist …

XY101 is a selective, metabolically stable and orally available agonist of RORγ inverse(IC50 of 30 …

SR2211 is a specific modulator and an inverse agonist of RORγ(IC50 = 320 nM, Ki …

AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment …

RORγt Inverse agonist 6 is an agonist of RORγt inverse. RORγt Inverse agonist 6 can …

Bevurogant is an antagonist of RORγt receptor and can be used in studies about the …

RORγt inverse agonist 14 (8e) is a potent, selective, and orally active compound with an …

ML-209 is an antagonist of retinoic acid receptor-related orphan receptor γt (RORγt; IC50= 1.1 μM …

TMP-778 is a selective inverse agonist of RORγt.

RORγt inverse agonist 31 (14g) is a potent antagonist of the retinoic acid receptor-related orphan …

GSK2981278 (ROR gama modulator 1) is a highly potent and selective inverse agonist of retinoic …

RORγt inverse agonist 13 (Compound 3i) is a potent, orally active and selective RORγt inverse …

1. Neoruscogenin represents a universal pharmacological tool for RORα research due to its specific selectivity …

Melatonin (Melatonine) is a biogenic amine that is found in animals and plants. In mammals, …

T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of …

3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) (Dehydrolithocholic acid) is a bile acid metabolite and inhibits the differentiation …

Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, …

Cedirogant (ABBV-157) is an orally active retinoid-related orphan receptor-γt(RORγt) inverse agonist that is used for …

Cintirorgon (LYC-55716) is a selective, oral agonist of RORγ. Cintirorgon modulates gene expression of RORγ …

SR0987 is a RORγt agonist,

SR 1001 is an inverse agonist for RORα/RORγ (Kis: 172/111 nM).

S18-000003 is an effective orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t inhibitor (IC50: 29 nM). …

Nobiletin (Hexamethoxyflavone) is a natural polymethoxylated flavone isolated from citrus peels with anti-inflammatory and anti-tumor …

SR3335 (ML 176) is a selective inverse agonist of RORα, competitively inhibiting the binding of …

SR1078 is an agonist of retinoic acid receptor-related orphan receptor (ROR)α/γ.

GSK805 is a potent, orally bioavailable retinoid-related orphan receptor gamma t (RORγt) inverse agonist that …

Zymostenol (5a-Cholest-8-en-3b-ol) is a RORγ agonist with an EC50 of 1 μM.Zymostenol is a late …

RORγt Inverse agonist 8 is a potent, selective, orally bioavailable RORγt inverse agonist(human RORγt-LBD with …

Methyl-3β-hydroxycholenate (Methyl 3beta-hydroxychol-5-enoate) is a modulator of RORγ.

FM26 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells. …

TMP780 is an inverse RORγt agonist (IC50: 13 nM). RORγt is a tractable drug target …

TAK-828F is a potent, selective, and orally available retinoic acid receptor-related orphan receptor γt (RORγt) …

A-9758 is a RORγ ligand and a selective RORγt inverse agonist (IC50: 5 nM) and …

Vimirogant is a RORγ inhibitor (Ki: <100 nM).